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Infobox references
Chemical compound
Thiomersal (INN), or thimerosal (USAN, JAN), also sold under the name merthiolate[4] is an organomercury compound. It is a well-established antiseptic and antifungal agent.[5]
The pharmaceutical corporation Eli Lilly and Company named it Merthiolate. It has been used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks.[6] In spite of the scientific consensus that fears about its safety are unsubstantiated,[7][8][9][10] its use as a vaccine preservative has been called into question by anti-vaccination groups. A statement issued by the American Academy of Pediatrics and the US Public Health Service in 1999 prompted the removal of thimerosal from many vaccines.[11][12][13] It remains in use as a preservative for annual flu vaccines.[14]
^Cite error: The named reference molstruct was invoked but never defined (see the help page).
^"Thimerosal T5125".
^Chambers, Michael. "ChemIDplus – 54-64-8 – RTKIYNMVFMVABJ-UHFFFAOYSA-L – Thimerosal [USP:JAN] – Similar structures search, synonyms, formulas, resource links, and other chemical information". chem.sis.nlm.nih.gov. Retrieved 3 April 2018.
^"Merthiolate poisoning: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 8 December 2023.
^"Thimerosal and Vaccines | Vaccine Safety | CDC". Centers for Disease Control and Prevention. 25 August 2020. Retrieved 4 May 2023.
^Sharpe, M. A.; Livingston, A. D.; Baskin, D. S. (2012). "Thimerosal-Derived Ethylmercury is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA". Journal of Toxicology. 2012: 1–12. doi:10.1155/2012/373678. PMC 3395253. PMID 22811707. ...widely used in medical products, including as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks...
^Immunization Safety Review Committee, Board on Health Promotion and Disease Prevention, Institute of Medicine (2004). Immunization Safety Review: Vaccines and Autism. Washington, DC: The National Academies Press. ISBN 978-0-309-09237-1.{{cite book}}: CS1 maint: multiple names: authors list (link)
^Doja, Asif; Roberts, Wendy (November 2006). "Immunizations and autism: a review of the literature". Can J Neurol Sci. 33 (4): 341–46. doi:10.1017/s031716710000528x. PMID 17168158.
^"Vaccines Do Not Cause Autism". cdc.gov. Retrieved 29 November 2015.
^Gołoś, A; Lutyńska, A (2015). "Thiomersal-containing vaccines - a review of the current state of knowledge". Przeglad Epidemiologiczny. 69 (1): 59–64, 157–61. PMID 25862449.
^"Thimerosal in Vaccines: A Joint Statement of the American Academy of Pediatrics and the Public Health Service" (PDF). Morbidity and Mortality Weekly Report Vol. 48 No. 26. Centers for Disease Control and Prevention. 9 July 1999. pp. 563–65. Retrieved 8 May 2024.
^Hurley, A; Tadrous, M; Miller, E (July–September 2010). "Thimerosal-Containing Vaccines and Autism: A Review of Recent Epidemiologic Studies". J Pediatr Pharmacol Ther. 15 (3): 173–181. PMC 3018252. PMID 22477809.
^Cite error: The named reference drugsaf was invoked but never defined (see the help page).
^"Not Immune". The New Yorker. 8 February 2015. Retrieved 2 October 2022.
Thiomersal (INN), or thimerosal (USAN, JAN), also sold under the name merthiolate is an organomercury compound. It is a well-established antiseptic and...
Thiomersal (or thimerosal) is a mercury compound which is used as a preservative in some vaccines. Anti-vaccination activists promoting the incorrect claim...
request vaccine makers to remove thiomersal from vaccines as quickly as possible on the precautionary principle. Thiomersal is now absent from all common...
the organomercury compound thiomersal (spelled "thimerosal" in the US) from vaccines as quickly as possible, and thiomersal has been phased out of US and...
Lilly has developed the vaccine preservative thiomersal (also called merthiolate and thimerosal). Thiomersal is effective by causing susceptible bacteria...
in laboratory work include sodium azide (which is acutely toxic) and thiomersal.[citation needed] Bacteriostatic antibiotics limit the growth of bacteria...
dimethylmercury, (CH3)2Hg, diethylmercury and merbromin ("Mercurochrome"). Thiomersal is used as a preservative for vaccines and intravenous drugs. The toxicity...
Group markets a chlorhexidine solution under the name Mercurochrome. Thiomersal, also known as Thimerosal or Merthiolate Nitromersol, an organomercury...
Several preservatives are available, including thiomersal, phenoxyethanol, and formaldehyde. Thiomersal is more effective against bacteria, has a better...
infants, children or adults exposed to thiomersal in vaccines". In 2008 a review noted that even though thiomersal was removed from all US childhood vaccines...
enhance the action of another preservative such as benzalkonium chloride or thiomersal) in ocular preparations and eyedrops. In medical diagnosis and organ function...
patients) to prevent contamination of the vaccine. Despite thiomersal's efficacy, the use of thiomersal is controversial because it can be metabolized or degraded...
variability, the health effects of tobacco, the alleged relation between thiomersal and autism, alleged negative side effects of the HPV vaccine, and evolution...
for a causal connection between thiomersal and autism, but parental concern about a relationship between thiomersal and vaccines has led to decreasing...
disproven theories blaming vaccine "overload", the vaccine preservative thiomersal, or the MMR vaccine for causing autism spectrum disorder. In 1998, British...
Weissman Controversy General MMR (Lancet MMR autism fraud) NCVIA Pox party Thiomersal Vaccines and SIDS Cedillo v. Secretary of Health and Human Services Alternative...
covalently bonded to an aromatic ring. The organosulfur ligand in the medicine thiomersal is a thiophenol. There are several methods of synthesis for thiophenol...
Weissman Controversy General MMR (Lancet MMR autism fraud) NCVIA Pox party Thiomersal Vaccines and SIDS Cedillo v. Secretary of Health and Human Services Alternative...
or sensitivity to a preservative. In the past, thiomersal was used as a preservative. In 1989, thiomersal was responsible for about 10% of problems related...
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