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Neuropharmacology information


Neuropharmacology is the study of how drugs affect function in the nervous system, and the neural mechanisms through which they influence behavior.[1] There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain.[2] Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.

  1. ^ Yeung AWK, Tzvetkov NT, Atanasov AG. When Neuroscience Meets Pharmacology: A Neuropharmacology Literature Analysis. Front Neurosci. 2018 Nov 16;12:852. doi: 10.3389/fnins.2018.00852.
  2. ^ Everitt, B. J.; Robbins, T. W. (2005). "Neural systems of reinforcement for drug addiction: from actions to habits to compulsion". Nature Neuroscience. 8 (11): 1481–1489. doi:10.1038/nn1579. PMID 16251991.

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Neuropharmacology

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Neuropharmacology is the study of how drugs affect function in the nervous system, and the neural mechanisms through which they influence behavior. There...

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Clinical Neuropharmacology

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The Clinical Neuropharmacology is a peer-reviewed bimonthly journal publishes original articles, brief reports, reviews devoted to the pharmacology of...

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Tea

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and physical performance enhancer or psychoactive drug?". Current Neuropharmacology. 13 (1): 71–88. doi:10.2174/1570159X13666141210215655. PMC 4462044...

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Phencyclidine

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and Addictive Disorders". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill...

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Methamphetamine

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trace amine associated receptor 1 cAMP signaling in astrocytes". Neuropharmacology. 85: 499–507. doi:10.1016/j.neuropharm.2014.06.011. PMC 4315503. PMID 24950453...

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Amphetamine

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Function and Behavioral Control". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York, US: McGraw-Hill...

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Dopamine

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Nestler EJ, Hyman SE (2009). Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill...

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Tryptamine

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"Recreational Use, Analysis and Toxicity of Tryptamines". Current Neuropharmacology. 13 (1): 26–46. doi:10.2174/1570159X13666141210222409. ISSN 1570-159X...

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Melatonin

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"Melatonin: Pharmacology, Functions and Therapeutic Benefits". Current Neuropharmacology. 15 (3): 434–443. doi:10.2174/1570159X14666161228122115. PMC 5405617...

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Alcohol intoxication

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Departments Vengeliene, V; Bilbao, A; Molander, A; Spanagel, R (2008). "Neuropharmacology of alcohol addiction". British Journal of Pharmacology. 154 (2): 299–315...

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Cannabidiol

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(September 13, 2019). "Cannabidiol Adverse Effects and Toxicity". Current Neuropharmacology. 17 (10). Bentham Science Publishers Ltd.: 974–989. doi:10...

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Psychoactive drug

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physical enhancement: revolving doors of cosmetic neurology". Current Neuropharmacology. 13 (1): 5–11. doi:10.2174/1570159X13666141210221750. PMC 4462043...

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Promethazine

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NMDA-induced currents - new pharmacological aspects of an old drug". Neuropharmacology. 63 (2): 280–291. doi:10.1016/j.neuropharm.2012.03.006. PMID 22507664...

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Inositol

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(Skin-picking) Disorder, and Nail-biting (Onychophagia)". Current Neuropharmacology. 17 (8): 775–786. doi:10.2174/1570159X17666190320164223. PMC 7059154...

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Outline of neuroscience

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structures of the nervous system. Immunostaining Category: Neuroanatomy Neuropharmacology is the study of how drugs affect cellular function in the nervous...

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Amitriptyline

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imipramine are weak antagonists of human and rat alpha1B-adrenoceptors". Neuropharmacology. 59 (1–2): 49–57. doi:10.1016/j.neuropharm.2010.03.015. PMID 20363235...

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Euphoria

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Nestler EJ, Hyman SE (2009). Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill...

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Oxytocin

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oxytocin, CCK, gastrin and somatostatin plasma levels in the rat". Neuropharmacology. 35 (11): 1635–1640. doi:10.1016/S0028-3908(96)00078-0. PMID 9025112...

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Minoxidil

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barrier permeability through ROS/RhoA/PI3K/PKB signaling pathway". Neuropharmacology. 75: 407–415. doi:10.1016/j.neuropharm.2013.08.004. PMID 23973310...

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Nandrolone

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impact of nandrolone decanoate on the central nervous system". Current Neuropharmacology. 13 (1): 122–31. doi:10.2174/1570159X13666141210225822. PMC 4462037...

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Dextroamphetamine

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Acetylcholine, and Orexin". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York, US: McGraw-Hill...

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Clonidine

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1987). "Alpha adrenoceptor modulation of the jaw-opening reflex". Neuropharmacology. 26 (7A): 649–655. doi:10.1016/0028-3908(87)90224-3. PMID 2819761...

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