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Neuropeptide B is a short biologically active peptide whose precursor in humans is encoded by the NBP gene. Neuropeptide B acts via two G protein-coupled receptors, neuropeptide B/W receptors, called NPBW1 and NPBW2 encoded by the genes NPBWR1 and NPBWR2, respectively. Neuropeptide B is thought to be associated with the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway.[5][6] It is expressed throughout the CNS with high levels in the substantia nigra, hypothalamus, hippocampus, and spinal cord.
^ abcGRCh38: Ensembl release 89: ENSG00000183979 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000044034 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Singh G, Davenport AP (Aug 2006). "Neuropeptide B and W: neurotransmitters in an emerging G-protein-coupled receptor system". British Journal of Pharmacology. 148 (8): 1033–41. doi:10.1038/sj.bjp.0706825. PMC 1752024. PMID 16847439.
^Hondo M, Ishii M, Sakurai T (2008). "The NPB/NPW Neuropeptide System and Its Role in Regulating Energy Homeostasis, Pain, and Emotion". Orphan G Protein-Coupled Receptors and Novel Neuropeptides. Results and Problems in Cell Differentiation. Vol. 46. pp. 239–56. doi:10.1007/400_2007_056. ISBN 978-3-540-78350-3. PMID 18204824.
NeuropeptideB is a short biologically active peptide whose precursor in humans is encoded by the NBP gene. NeuropeptideB acts via two G protein-coupled...
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from inactive apo to fully active have been obtained. Unlike Class A and B GPCRs, phospholipids bind within the transmembrane bundles and allosteric...
phototransduction". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364 (1531): 2881–2895. doi:10.1098/rstb.2009.0051. PMC 2781858...
The neuropeptide FF receptors are members of the G-protein coupled receptor superfamily of integral membrane proteins which bind the pain modulatory neuropeptides...
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Neuropeptide FF receptor 2, also known as NPFF2 is a human protein encoded by the NPFFR2 gene. Neuropeptide FF receptor GRCh38: Ensembl release 89: ENSG00000056291...
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Francisco: Pearson Benjamin Cummings. ISBN 978-0-8053-5910-7. Zimmerberg, B. 2002. Dopamine receptors: A representative family of metabotropic receptors...
ligands in structure-based virtual screening studies. The expression of NF-κB, the transcription factor that regulates inflammatory processes, is promoted...
Oroshnik W (June 1956). "The Synthesis and Configuration of Neo-B Vitamin A and Neoretinine b". Journal of the American Chemical Society. 78 (11): 2651–2652...