adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
regulation of sensory perception of pain
locomotory behavior
positive regulation of cytosolic calcium ion concentration
positive regulation of peptide secretion
outflow tract morphogenesis
cardiac left ventricle morphogenesis
negative regulation of nervous system process
negative regulation of synaptic transmission
behavioral fear response
negative regulation of excitatory postsynaptic potential
secretion
positive regulation of circadian sleep/wake cycle, non-REM sleep
positive regulation of dopamine secretion
negative regulation of secretion
feeding behavior
negative regulation of feeding behavior
nitric oxide mediated signal transduction
neuropeptide signaling pathway
positive regulation of smooth muscle contraction
negative regulation of synaptic transmission, glutamatergic
signal transduction
positive regulation of cell-substrate adhesion
human ageing
chemical synaptic transmission
G protein-coupled receptor signaling pathway
negative regulation of cAMP-mediated signaling
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4887
18167
Ensembl
ENSG00000185149
ENSMUSG00000028004
UniProt
P49146
P97295
RefSeq (mRNA)
NM_000910 NM_001370180 NM_001375470
NM_001205099 NM_008731
RefSeq (protein)
NP_000901 NP_001357109 NP_001362399
NP_001192028 NP_032757
Location (UCSC)
Chr 4: 155.21 – 155.22 Mb
Chr 3: 82.45 – 82.46 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Neuropeptide Y receptor type 2 (Y2R) is a member of the neuropeptide Y receptor family of G-protein coupled receptors, that in humans is encoded by the NPY2R gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000185149 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028004 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Rose PM, Fernandes P, Lynch JS, Frazier ST, Fisher SM, Kodukula K, Kienzle B, Seethala R (Sep 1995). "Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor". The Journal of Biological Chemistry. 270 (39): 22661–4. doi:10.1074/jbc.270.39.22661. PMID 7559383.
^"Entrez Gene: NPY2R neuropeptide Y receptor Y2".
and 12 Related for: Neuropeptide Y receptor Y2 information
NeuropeptideYreceptors are a family of receptors belonging to class A G-protein coupled receptors and they are activated by the closely related peptide...
communication. NeuropeptideY is expressed in interneurons. NPY exerts most of its effects through NeuropeptideYreceptors, mainly Y1, Y2, Y4, and Y6....
NeuropeptideYreceptor type 1 is a protein that in humans is encoded by the NPY1R gene. NeuropeptideY (endogenous agonist, non subtype selective) Peptide...
NeuropeptideYreceptor type 5 is a protein that in humans is encoded by the NPY5R gene. NeuropeptideY (endogenous agonist, non subtype selective) BWX-46...
VGF Exogenous Lifitegrast (LFA-1 antagonist) Neuropeptidereceptor Neurotransmitter receptor Peptide+receptor at the U.S. National Library of Medicine Medical...
PYY immunoreactivity is PYY3-36, which binds to the Y2receptor (Y2R) of the Y family of receptors. Peptide YY3-36 (PYY) is a linear polypeptide consisting...
(October 2021). "The effect of fatty diacid acylation of human PYY3-36 on Y2receptor potency and half-life in minipigs". Scientific Reports. 11 (1): 21179...
Tsunashima K, Schwarzer C, Takahashi Y, Kato N, Sperk G (1998). "Trimethyltin-induced expression of neuropeptideYY2receptors in rat dentate gyrus". Neurotoxicol...