Peptides released by neurons as intercellular messengers
Neuropeptide Y
Neuropeptides are chemical messengers made up of small chains of amino acids that are synthesized and released by neurons. Neuropeptides typically bind to G protein-coupled receptors (GPCRs) to modulate neural activity and other tissues like the gut, muscles, and heart.
Neuropeptides are synthesized from large precursor proteins which are cleaved and post-translationally processed then packaged into dense core vesicles. Neuropeptides are often co-released with other neuropeptides and neurotransmitters in a single neuron, yielding a multitude of effects. Once released, neuropeptides can diffuse widely to affect a broad range of targets.
Neuropeptides are chemical messengers made up of small chains of amino acids that are synthesized and released by neurons. Neuropeptides typically bind...
Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral...
Neuropeptide K (also known as neurokinin K), is a protein encoded by the TAC1 gene. It is an elongated derivative of the N-terminus of neurokinin A as...
Neuropeptide B is a short biologically active peptide whose precursor in humans is encoded by the NBP gene. Neuropeptide B acts via two G protein-coupled...
NPFF Neuropeptide FF (FLFQPQRFa) is a mammalian amidated neuropeptide originally isolated from bovine brain and characterized as a pain-modulating peptide...
Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus...
Neuropeptide Y receptors are a family of receptors belonging to class A G-protein coupled receptors and they are activated by the closely related peptide...
Neuropeptide W or preprotein L8 is a short human neuropeptide. Neuropeptide W acts as a ligand for two neuropeptide B/W receptors, NPBWR1 and NPBWR2,...
The neuropeptide FF receptors are members of the G-protein coupled receptor superfamily of integral membrane proteins which bind the pain modulatory neuropeptides...
The neuropeptide S receptor (NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S (NPS)...
acetylcholine, histamine, norepinephrine, nitric oxide, and several neuropeptides. Cannabinoids can also be powerful CNS neuromodulators. Neuromodulators...
GPCR neuropeptide receptors are G-protein coupled receptors which bind various neuropeptides. Members include: Neuropeptide B/W receptor NPBWR1 NPBWR2...
Neuropeptide Y receptor type 5 is a protein that in humans is encoded by the NPY5R gene. Neuropeptide Y (endogenous agonist, non subtype selective) BWX-46...
Neuropeptide FF receptor 1, also known as NPFF1 is a human protein, encoded by the NPFFR1 gene. Neuropeptide FF receptor GRCh38: Ensembl release 89: ENSG00000148734...
Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene. Neuropeptide Y (endogenous agonist, non subtype selective) Peptide...
Neuropeptide FF receptor 2, also known as NPFF2 is a human protein encoded by the NPFFR2 gene. Neuropeptide FF receptor GRCh38: Ensembl release 89: ENSG00000056291...
precursor for a neuropeptide gene, nesfatin-1, has also been found in Tunicaraptor unikontum. These discoveries suggest that neuropeptide signaling in animals...
about 50 residues; a variable-length region; and the sequence of the neuropeptides themselves. Sequence analysis reveals that the conserved N-terminal...
cell membrane Corticotropin-like intermediate peptide, an endogenous neuropeptide Cross-linking immunoprecipitation, a method used in molecular biology...
A neuropeptide receptor is a type of peptide receptor which binds one or more neuropeptides. An example is the μ-opioid receptor, which binds to and is...
Putative neuropeptide Y receptor type 6 is a protein that in humans is encoded by the NPY6R gene. GRCh38: Ensembl release 89: ENSG00000226306 – Ensembl...
roles both as a neuropeptide in the central nervous system and as a peptide hormone in the gut. It is the most abundant neuropeptide in the central nervous...
neurotransmitters and other molecules such as psychopharmaceuticals and neuropeptides, that control and influence the physiology of the nervous system. This...
adjacent cells Neuropeptide, a protein sequence which acts as a hormone or neurotransmitter. The blood or other body fluids transport neuropeptides to non adjacent...
of serotonin is the amino acid tryptophan. Peptide transmitters, or neuropeptides, are protein transmitters that often are released together with other...
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