detection of chemical stimulus involved in sensory perception of sweet taste
signal transduction
response to stimulus
G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
80834
83770
Ensembl
ENSG00000179002
ENSMUSG00000028738
UniProt
Q8TE23
Q925I4
RefSeq (mRNA)
NM_152232
NM_031873
RefSeq (protein)
NP_689418
NP_114079
Location (UCSC)
Chr 1: 18.84 – 18.86 Mb
Chr 4: 139.38 – 139.4 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
T1R2 - Taste receptor type 1 member 2 is a protein that in humans is encoded by the TAS1R2 gene.[5]
The sweet taste receptor is predominantly formed as a dimer of T1R2 and T1R3 by which different organisms sense this taste. In songbirds, however, the T1R2 monomer does not exist, and they sense the sweet taste through the umami taste receptor (T1R1 and T1R3) as a result of an evolutionary change that it has undergone.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000179002 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028738 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: TAS1R2 taste receptor, type 1, member 2".
^Toda Y, Ko MC, Liang Q, Miller ET, Rico-Guevara A, Nakagita T, et al. (July 2021). "Early origin of sweet perception in the songbird radiation". Science. 373 (6551): 226–231. Bibcode:2021Sci...373..226T. doi:10.1126/science.abf6505. PMID 34244416. S2CID 235769720.
receptor type 1 member 2 is a protein that in humans is encoded by the TAS1R2 gene. The sweet taste receptor is predominantly formed as a dimer of T1R2...
families:[citation needed] Type 1, sweet, first characterized in 2001: TAS1R2 – TAS1R3 Type 2, bitter, first characterized in 2000: In humans there are...
TAS1R1+3 and sweet taste receptor TAS1R2+3. This receptor is formed as a protein dimer with either TAS1R1 or TAS1R2. Experiments have also shown that...
individuals for the umami taste. Another interesting quality of the TAS1R1 and TAS1R2 proteins is their spontaneous activity in the absence of the extracellular...
lack the TAS1R2 protein, one of two required for function of the sweetness sensory receptor. This is due to a deletion in the relevant gene (Tas1r2) causes...
washing, or coating themselves in their own urine. Megabats possess the TAS1R2 gene, meaning they have the ability to detect sweetness in foods. This gene...
water tastes slightly sweet to humans, with the effect mediated by the TAS1R2/TAS1R3 taste receptor. Rats given a choice between distilled normal water...
It has an intense sweet taste because it stimulates the sweet receptor TAS1R2+TAS1R3 in humans, although this is species-dependent, as the equivalent...
Taste receptor, type 1, member 1 (TAS1R1) Taste receptor, type 1, member 2 (TAS1R2) Taste receptor, type 1, member 3 (TAS1R3) Class C Orphan receptors GPR158...
binding of the heterodimer G protein-coupled receptor formed by the proteins TAS1R2 and TAS1R3. Rodents do not experience aspartame as sweet-tasting, due to...
TR.2, see Orenda Engines TR2, a postal district in the TR postcode area TAS1R2, a taste receptor Temple Run 2 Westinghouse TR-2 research reactor operated...
saltiness, sourness, bitterness, sweetness, and umami, are the cell-bound GPRs TAS1R2/TAS1R3, TAS1R1/TAS1R3, and multiple subtypes of TAS2R for sweetness, umami...
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