Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function.[1] There are various forms,[2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., heparin, lithium).
^Abyar, Selda; Khandar, Ali Akbar; Salehi, Roya; Abolfazl Hosseini-Yazdi, Seyed; Alizadeh, Effat; Mahkam, Mehrdad; Jamalpoor, Amer; White, Jonathan M.; Shojaei, Motahhareh; Aizpurua-Olaizola, O.; Masereeuw, Rosalinde (December 2019). "In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes". Scientific Reports. 9 (1): 14686. Bibcode:2019NatSR...914686A. doi:10.1038/s41598-019-51109-9. ISSN 2045-2322. PMC 6789105. PMID 31604983.
^Galley HF (2000). "Can acute renal failure be prevented". J R Coll Surg Edinb. 45 (1): 44–50. PMID 10815380. Archived from the original on 2005-10-18.
in more than one way. Nephrotoxins are substances displaying nephrotoxicity. Nephrotoxicity should not be confused with some medications predominantly excreted...
suggest that the herb may have some toxic properties towards kidneys (nephrotoxicity). American composer David Woodard, who cultivated Calea ternifolia on...
(seronegative) rheumatoid arthritis or ankylosing spondylitis. Fluoride induced nephrotoxicity is kidney injury due to toxic levels of serum fluoride, commonly due...
mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway". Anesthesiology...
further research is required in this area. Other precautions include: nephrotoxicity, sulfonamide (sulfa) allergy, and increases free thyroid hormone effects...
individuals. Other side effects include nephrotoxicity, neuromuscular toxicity, and hypersensitivity reactions. Nephrotoxicity can be particularly worrisome when...
risk can be minimized by reducing the duration of use. Amikacin causes nephrotoxicity (damage to the kidneys), by acting on the proximal renal tubules. It...
of the most nephrotoxic drugs of this class. Oftentimes, acute nephrotoxicity is reversible, but it may be fatal. The risk of nephrotoxicity can be affected...
factor for upper-extremity deep-vein thrombosis. Damage to the kidneys (nephrotoxicity) and to the hearing (ototoxicity) were side effects of the early impure...
36. doi:10.2460/javma.2002.220.49. PMID 12680447. Hall J (1992). "Nephrotoxicity of Easter Lily (Lilium longiflorum) when ingested by the cat". Proc...
2017. Retrieved 31 August 2017. Luciano RL, Perazella MA (June 2014). "Nephrotoxic effects of designer drugs: synthetic is not better!". Nature Reviews...
found to increase the plasma concentrations of methotrexate, as have nephrotoxic agents such as cisplatin, the GI drug colestyramine, and dantrolene....
does not flow from the liver to the intestine) and liver fibrosis. Nephrotoxicity (kidney damage) can be caused by tumor lysis syndrome and also due direct...
pigs in large amounts over several days. Such forage may cause fatal nephrotoxicity, presumably because of its high oxalate content. Other symptoms, such...
investigation into potential correlation of sevoflurane use and renal damage (nephrotoxicity). However, this should be subject to further investigation, as a recent...
serious infections (including Clostridium difficile), and kidney damage (nephrotoxicity). A rare, though less understood, side effect of the PPI class is the...
and Cotard's syndrome. Intravenous aciclovir may cause reversible nephrotoxicity in up to 5% to 10% of patients because of precipitation of aciclovir...
include nausea and vomiting, hair loss, tinnitus, hearing loss, and nephrotoxicity.) Organoplatinum compounds such as the above antitumour agents, as well...
should be used with caution in patients with colitis, as it is both nephrotoxic and ototoxic. Absorption through the damaged wall of the intestinal tract...
injected in large doses; precipitation of this hydroxide resulted in nephrotoxicity in animals. In lower doses, soluble gallium is tolerated well and does...
of toxicity that have been studied for citrinin are acute toxicity, nephrotoxicity, genotoxicity and its carcinogenicity. The acute toxicity of citrinin...
leaves themselves contain notable quantities of oxalic acid, which is a nephrotoxic and corrosive acid present in many plants. Symptoms of poisoning include...
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