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Cephalosporin information


Cephalosporin
Drug class
Core structure of the cephalosporins
Class identifiers
UseBacterial infection
ATC codeJ01D
Biological targetPenicillin binding proteins
Clinical data
Drugs.comDrug Classes
External links
MeSHD002511
Legal status
In Wikidata
Structure of the classical cephalosporins

The cephalosporins (sg. /ˌsɛfələˈspɔːrɪn, ˌkɛ-, -l-/[1][2]) are a class of β-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as Cephalosporium.[3]

Together with cephamycins, they constitute a subgroup of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964.[4]

  1. ^ "cephalosporin". Merriam-Webster.com Dictionary.
  2. ^ "cephalosporin – definition of cephalosporin in English from the Oxford dictionary". OxfordDictionaries.com. Archived from the original on 7 July 2012. Retrieved 20 January 2016.
  3. ^ "cephalosporin" at Dorland's Medical Dictionary
  4. ^ Oxford Handbook of Infectious Diseases and Microbiology. OUP Oxford. 2009. p. 56. ISBN 9780191039621.

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Cephalosporin

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The cephalosporins (sg. /ˌsɛfələˈspɔːrɪn, ˌkɛ-, -loʊ-/) are a class of β-lactam antibiotics originally derived from the fungus Acremonium, which was previously...

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Cephalosporin C

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Cephalosporin C is an antibiotic of the cephalosporin class. It was isolated from a fungus of the genus Acremonium and first characterized in 1961. Although...

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Cefuroxime

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sold under the brand name Zinacef among others, is a second-generation cephalosporin antibiotic used to treat and prevent a number of bacterial infections...

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Discovery and development of cephalosporins

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Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with...

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Cefalexin

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Cefalexin is a β-lactam antibiotic within the class of first-generation cephalosporins. It works similarly to other agents within this class, including intravenous...

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Cefdinir

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to be safe but has not been well studied. It is a third-generation cephalosporin and works by interfering with a bacteria's ability to make a cell wall...

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List of antibiotics

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Pseudomonas aeruginosa: Certain cephalosporins, cephalosporin-beta-lactamase-inhibitor combinations, and new siderophore cephalosporins. Ceftazidime (3rd generation)...

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Cefuroxime axetil

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under the brand name Ceftin among others, is a second generation oral cephalosporin antibiotic. It is an acetoxyethyl ester prodrug of cefuroxime which...

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Cefazolin

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Cefazolin, also known as cefazoline and cephazolin, is a first-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections...

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Cefadroxil

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(formerly trademarked as Duricef) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections...

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Cefixime

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be relatively safe during pregnancy. It is in the third-generation cephalosporin class of medications. It works by disrupting the bacteria's cell wall...

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Ceftriaxone

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Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections...

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Ceftazidime

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sold under the brand name Fortaz among others, is a third-generation cephalosporin antibiotic useful for the treatment of a number of bacterial infections...

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Cefoperazone

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Cefoperazone is a third-generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid. It is one of few cephalosporin antibiotics effective in...

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Cefpodoxime

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Cefpodoxime is an oral, third-generation cephalosporin antibiotic available in various generic preparations. It is active against both Gram-positive and...

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Edward Abraham

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instrumental in the development of the first antibiotics penicillin and cephalosporin. Abraham was born on 10 June 1913 at 47 South View Road, Shirley, Southampton...

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Cefepime

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Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria...

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Cefovecin

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Cefovecin (INN) is an antibiotic of the cephalosporin class, licensed for the treatment of skin infections in cats and dogs. It is marketed by Zoetis...

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Avibactam

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resistant Gram-negative bacterial pathogens. Increasing resistance to cephalosporins among Gram-(−) bacterial pathogens, especially among hospital-acquired...

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Nectar Lifesciences

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products. The company has global leadership in several oral and sterile cephalosporin drugs, and has cGMP facilities along with those approved by the European...

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Cefotaxime

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use during pregnancy and breastfeeding. It is in the third-generation cephalosporin family of medications and works by interfering with the bacteria's cell...

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Mycology

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exposed to ultraviolet (UV) light. Penicillin, ciclosporin, griseofulvin, cephalosporin and psilocybin are examples of drugs that have been isolated from molds...

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Cefditoren

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and is in the cephalosporin family of antibiotics, which is part of the broader beta-lactam group of antibiotics. Like other cephalosporins, cefditoren...

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Antibiotic resistance in gonorrhea

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mutations to the gyrA gene, which encodes DNA gyrase. Third-generation cephalosporins have been used to treat gonorrhoea since 2007, but resistant strains...

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