negative regulation of cell population proliferation
protein folding
regulation of signaling receptor activity
reproductive process
cGMP-mediated signaling
positive regulation of cGMP-mediated signaling
negative regulation of collagen biosynthetic process
negative regulation of DNA biosynthetic process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4880
18159
Ensembl
ENSG00000163273
ENSMUSG00000026241
UniProt
P23582
Q61839
RefSeq (mRNA)
NM_024409
NM_010933
RefSeq (protein)
NP_077720
NP_035063
Location (UCSC)
Chr 2: 231.92 – 231.93 Mb
Chr 1: 86.59 – 86.6 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Natriuretic peptide precursor C, also known as NPPC, is a protein that in humans is encoded by the NPPC gene.[5][6][7] The precursor NPPC protein is cleaved to the 22 amino acid peptide C-type natriuretic peptide (CNP).
^ abcGRCh38: Ensembl release 89: ENSG00000163273 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000026241 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kaneko T, Shirakami G, Nakao K, Nagata I, Nakagawa O, Hama N, Suga S, Miyamoto S, Kubo H, Hirai O (May 1993). "C-type natriuretic peptide (CNP) is the major natriuretic peptide in human cerebrospinal fluid". Brain Research. 612 (1–2): 104–9. doi:10.1016/0006-8993(93)91649-D. PMID 8330189. S2CID 41367489.
^Ogawa Y, Itoh H, Yoshitake Y, Inoue M, Yoshimasa T, Serikawa T, Nakao K (November 1994). "Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC)". Genomics. 24 (2): 383–7. doi:10.1006/geno.1994.1633. PMID 7698765.
and 22 Related for: Natriuretic peptide precursor C information
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intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28...
same peptides, depending on the organism. In addition to the precursorpeptide sequences, prepropeptides also contain a signal peptide, spacer peptides, and...
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metalloproteinase-mediated shedding. Corin converts the atrial natriureticpeptide (ANP) precursor, pro-ANP, to mature ANP, a cardiac hormone that regulates...
liver and is a precursor for angiotensin, but has also been indicated as having many other roles not related to angiotensin peptides. It is a member...
Neuropeptide VF precursor, also known as pro-FMRFamide-related neuropeptide VF or RFamide-related peptideprecursor, is a propeptide that in mammals is...
Atrial natriureticpeptide (CDD/ANP-99-126) is a hormone system of clinical importance. Urodilatin (CDD/ ANP-95-126) is a homologue natriureticpeptide that...
acid derivatives (e.g. epinephrine and auxin), protein or peptides (e.g. insulin and CLE peptides), and gases (e.g. ethylene and nitric oxide). Hormones...
endocrine tumours. The PPY gene encodes an unusually short protein precursor. This precursor is cleaved to produce pancreatic polypeptide, pancreatic icosapeptide...
Bell GI, Sample C, Rubenstein AH, Steiner DF (November 1988). "An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing"...
its general pressor and pro-volumic effects on the body. Atrial natriureticpeptide inhibits AVP secretion, in part by inhibiting Angiotensin II-induced...
findings in a C. elegans model system with engineered polyglutamine peptides. Other polypeptides and proteins such as amylin and the β amyloid peptide do not...
Copeptin (also known as CT-proAVP) is a 39-amino acid-long peptide derived from the C-terminus of pre-pro-hormone of arginine vasopressin, neurophysin...
related protein hormone precursors including islet amyloid precursor protein, calcitonin gene-related peptide, and the precursor of adrenomedullin. Secretion...
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