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RFamide peptide family information


The RFamide peptide family, or the RFamide-related peptides (RFRPs), are a family of neuropeptides.[1][2] They are characterized by the possession of an Arg-Phe-NH2 motif at their C-terminal extremities.[1][2]

Members of the family include:[1][2]

  • Neuropeptide FF group
    • Neuropeptide AF
    • Neuropeptide FF
    • Neuropeptide SF (RFRP-1)
    • Neuropeptide VF (RFRP-3) (GnIH - avian species)
  • Prolactin-releasing peptide (PrRP)
  • Pyroglutamylated RFamide peptide (QRFP)
  • Kisspeptin (disputed)[3]
  1. ^ a b c Abba Kastin; Abba J. Kastin (28 April 2011). Handbook of Biologically Active Peptides. Academic Press. pp. 779–. ISBN 978-0-08-046379-7.
  2. ^ a b c Findeisen, Maria; Rathmann, Daniel; Beck-Sickinger, Annette G. (2011). "RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential". Pharmaceuticals. 4 (9): 1248–1280. doi:10.3390/ph4091248. ISSN 1424-8247. PMC 4058657.
  3. ^ Yun S, Kim DK, Furlong M, Hwang JI, Vaudry H, Seong JY (2014). "Does Kisspeptin Belong to the Proposed RF-Amide Peptide Family?". Front Endocrinol (Lausanne). 5: 134. doi:10.3389/fendo.2014.00134. PMC 4131245. PMID 25165463.

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RFamide peptide family

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The RFamide peptide family, or the RFamide-related peptides (RFRPs), are a family of neuropeptides. They are characterized by the possession of an Arg-Phe-NH2...

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QRFP

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(2004). "Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity". Proc. Natl. Acad. Sci. U.S.A. 100 (25):...

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Neurotransmitter

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peptides. Monoamines are synthesized by altering a single amino acid. For example, the precursor of serotonin is the amino acid tryptophan. Peptide transmitters...

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Kisspeptin

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These N-terminally truncated peptides are known as the kisspeptins and belong to a larger family of peptides known as RFamides which all share a common...

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Trichoplax

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Placozoa) has cells that react with antibodies against the neuropeptide RFAmide." in: Acta Zoologica. Blackwell Science, Oxford 74:2, (1993), p. 115, ISSN 0001-7272...

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FMRFamide

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(H-Phe-Met-Arg-Phe-NH2) is a neuropeptide from a broad family of FMRFamide-related peptides (FaRPs) all sharing an -RFamide sequence at their C-terminus. First identified...

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