Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease.[1]Drug-loaded polymeric micelle formed from self-assembly of amphiphilic block copolymers in aqueous media.Drug-loaded polymeric micelles with various targeting functions. (A) Antibody-targeted micelles (B) ligand-targeted micelles (C) Micelles with cell-penetrating function.
A nanocarrier is nanomaterial being used as a transport module for another substance, such as a drug. Commonly used nanocarriers include micelles, polymers, carbon-based materials, liposomes and other substances.[2] Nanocarriers are currently being studied for their use in drug delivery and their unique characteristics demonstrate potential use in chemotherapy. This class of materials was first reported by a team of researchers of University of Évora, Alentejo in early 1960's, and grew exponentially in relevance since then. [2]
^Torchilin, V (2006). "Multifunctional nanocarriers". Advanced Drug Delivery Reviews. 58 (14): 1532–55. doi:10.1016/j.addr.2006.09.009. PMID 17092599.
^ abQian W, Sun D, Zhu R, Du X, Liu H, Wang S. pH-sensitive strontium carbonate nanoparticles as new anticancer vehicles for controlled etoposide release. International Journal of Nanomedicine. 2012;7:5781-5792.
A nanocarrier is nanomaterial being used as a transport module for another substance, such as a drug. Commonly used nanocarriers include micelles, polymers...
prodrug therapies (ADEPTs, VDEPTs, GDEPTs) and proposed nanoparticle- or nanocarrier-linked drugs can understandably be Sequential Mixed-Type prodrugs. To...
chemical or enzymatic inactivation, etc.) Lipid-based, ligand-coated nanocarriers can store their payload in the hydrophobic shell or the hydrophilic interior...
of polyaspartic acid has been exploited for targeting of drug-loaded nanocarriers to bone. Preparation of hydrogels based on polyaspartic acid, in a variety...
absorption of biomacromolecules, i.e. pharmaceuticals, and function like a nanocarrier. Its effects on skin depend on the hyaluronate formulation and skin health:...
substructures from drugs, auxiliary agents, and even from the surface of nanocarriers, this enzyme enables the design of drug delivery systems that can alter...
marrow and nerve cells would help myelin recovery. Currently, several nanocarriers strategies are being developed for improving vitamin B12 delivery with...
Herrera-Alonso M, et al. (August 2012). "Effects of block copolymer properties on nanocarrier protection from in vivo clearance". Journal of Controlled Release. 162...
Marvel J, Kamada K, Andraud C, Baldeck PL, Parola S (November 2013). "Nanocarriers with ultrahigh chromophore loading for fluorescence bio-imaging and photodynamic...
possibility to develop new therapeutics. The ability to incorporate drugs into nanocarriers offers a new prototype in drug delivery that could hold great promise...
associated targeting vector onto nanocarrier to achieve recognition and binding; the size scale of the nanocarriers will also be engineered to reach the...
Synthesis of the dendritic supramolecules and their applications as nanocarrier agents (2005) Doctoral advisor Hassan Namazi Other academic advisors...
"In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers". Nature Nanotechnology. 12 (8): 813–820. doi:10.1038/nnano.2017.57....
Virion surfaces are functionalized and used to assemble nanoparticles Nanocarriers Virions are used to transport cargo compounds Nanoreactors Enzymes are...
aspect to consider when choosing the appropriate nanoparticle chemistry. Nanocarriers composed of biodegradable polymers undergo hydrolysis in the body, producing...
fenestrated endothelium, the nanocarrier size (10–100 nm, with greater retention in tumors seen in using larger nanocarriers) and charge (anionic or neutral)...
barium titanate nanoparticles (BTNPs) have been recently employed as nanocarriers for drug delivery. Magnetoelectric effect of giant strengths have been...
of the nanocarrier. The smaller the nanocarrier, the better the delivery properties and the solubility of the nutraceuticals; the nanocarrier is able...
understanding on how to develop more effective nanoparticles. "smart release" nanocarriers that can penetrate biofilms and be triggered by pathogenic microenvironments...
Csaba N, Garcia-Fuentes M, Alonso MJ (July 2006). "The performance of nanocarriers for transmucosal drug delivery". Expert Opinion on Drug Delivery. 3 (4):...
proteomic analysis, multifunctional magnetic/fluorescent nanoprobes, nanocarrier for in vivo drug delivery, nanospectroscopies will be developed. Integrated...
targeting ligands, allowing for multimodal theranostic approaches. These nanocarriers can enhance drug stability, improve drug solubility, and enable controlled...
"Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers". Journal of Controlled Release. 130...
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