The mumps virus (MuV) is the virus that causes mumps. MuV contains a single-stranded, negative-sense genome made of ribonucleic acid (RNA). Its genome is about 15,000 nucleotides in length and contains seven genes that encode nine proteins. The genome is encased by a capsid that is in turn surrounded by a viral envelope. MuV particles, called virions, are pleomorphic in shape and vary in size from 100 to 600 nanometers in diameter. One serotype and twelve genotypes that vary in their geographic distribution are recognized. Humans are the only natural host of the mumps virus.
MuV replicates first by binding to the surface of cells, whereby its envelope merges with the host cell membrane to release the capsid inside of the cell. Once inside, the viral RNA-dependent RNA polymerase transcribes messenger RNA (mRNA) from the genome and later replicates the genome. After translation of viral proteins, virions are formed adjacent to the cell membrane, where they then leave the cell by budding from its surface, using the cell membrane as the envelope.
The mumps virus was first identified as the cause of mumps in 1934 and was first isolated in 1945. Within a few years after isolation, vaccines protecting against MuV infection had been developed. MuV was first recognized as a species in 1971, and it has been given the scientific name Mumps orthorubulavirus. It is assigned to the genus Orthorubulavirus in the subfamily Rubulavirinae, family Paramyxoviridae.
^"ICTV Taxonomy history: Mumps orthorubulavirus". International Committee on Taxonomy of Viruses. Retrieved 18 May 2021.
The mumpsvirus (MuV) is the virus that causes mumps. MuV contains a single-stranded, negative-sense genome made of ribonucleic acid (RNA). Its genome...
Mumps is a highly contagious viral disease caused by the mumpsvirus. Initial symptoms of mumps are non-specific and include fever, headache, malaise...
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The MMR vaccine is a vaccine against measles, mumps, and rubella (German measles), abbreviated as MMR. The first dose is generally given to children around...
disease, rabies, polio, mumps, and measles. The International Committee on Taxonomy of Viruses (ICTV) classifies RNA viruses as those that belong to Group...
of aseptic meningitis (the other usual suspects being echovirus and mumpsvirus). The entry of coxsackievirus into cells, especially endothelial cells...
infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. Examples...
viruses include the following: parainfluenza virus (hPIV) and mumpsvirus (MuV), and examples of the bat-borne viruses are: Mapuera (MapV), Bat Mumps...
of live attenuated vaccines are measles, mumps, rubella, yellow fever, and some influenza vaccines. Viruses may be attenuated using the principles of...
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Ebola and Marburg viruses are well known members of this group, along with influenza virus, measles, mumps and rabies. All viruses that encode a reverse...
sores; less commonly type 1), varicella zoster virus (known for causing chickenpox and shingles), mumpsvirus, HIV, LCMV, Arboviruses (acquired from a mosquito...
(middle ultraviolet), a form of electromagnetic radiation Mumpsvirus (MuV), the virus that causes mumps MUV Interactive, the developer of Bird human-wearable...
prompted a virologist colleague of theirs to inject embryonated eggs with mumpsvirus. The chicks at first showed the changes of myocarditis, about a year...
virus, human respiratory syncytial virus, measles virus, mumpsvirus, Nipah virus, and rabies virus. Important pathogens of nonhuman animals and plants...
disease. Mumps hemagglutinin-neuraminidase: a kind of hemagglutinin that the mumpsvirus (MuV) produces, which is the virus that causes mumps. Hemagglutinin...
"ballooning" of the cells, typically human fibroblasts. Some viruses, such as mumpsvirus cause red blood cells from chickens to firmly attach to the infected...
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals...
The history of virology – the scientific study of viruses and the infections they cause – began in the closing years of the 19th century. Although Edward...
Jeryl Lynn are strains of mumpsvirus used in the Mumpsvax mumps vaccine made by Merck. The strains are named after Jeryl Lynn Hilleman. In 1963, Jeryl's...
developed world viruses are believed to be the cause of about 85% of cases. Viral causes include coxsackievirus, herpesvirus, mumpsvirus, and HIV among...
A neurotropic virus is a virus that is capable of infecting nerve tissue. A neurotropic virus is said to be neuroinvasive if it is capable of accessing...
caused by a single-stranded RNA virus of the family Paramyxoviridae (the same family of viruses that causes measles, mumps, and bronchiolitis in humans)...
attenuated virus vaccine was licensed. In the early 1970s, a triple vaccine containing attenuated measles, mumps and rubella (MMR) viruses was introduced...
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