Cell shape changes as a function of mitotic phase. Shown is an example of a HeLa cell cultured on a glass surface. For visualization of DNA and mitotic phase assignment, the cell expresses Histone H2B-GFP to provide fluorescent labeling of chromosomes. Transmitted light (DIC), fluorescence (GFP), and merged images are shown every 4 minutes as the cell transitions from G2 phase through mitosis to telophase/G1 phase.
Mitotic cell rounding is a shape change that occurs in most animal cells that undergo mitosis. Cells abandon the spread or elongated shape characteristic of interphase and contract into a spherical morphology during mitosis. The phenomenon is seen both in artificial cultures in vitro and naturally forming tissue in vivo.
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Mitoticcellrounding is a shape change that occurs in most animal cells that undergo mitosis. Cells abandon the spread or elongated shape characteristic...
capture chromosomes. Therefore, mitoticcellrounding is thought to play a protective role in ensuring accurate mitosis. Rounding forces are driven by reorganization...
hysteresis in this cell cycle transition. At the intermediate cyclin B concentrations, either the interphase or mitotic state of the cell is possible. Since...
as the amoeba, one cell division is equivalent to reproduction – an entire new organism is created. On a larger scale, mitoticcell division can create...
blocking the formation of the mitotic spindles that attach to and pull apart sister chromatids in dividing cells. Cells will remain arrested until the...
lineage specifiers. It is also clear that pro-mitotic factors such as C-MYC/L-MYC or repression of cell cycle checkpoints, such as p53, are conduits to...
regulate HeLa cell cycle progression. Mitosis was found to be the most temperature-sensitive part of the cell cycle. Pre-cytokinesis mitotic arrest was visible...
kinases (PSKs/TAOKs) are activated in mitosis and contribute to mitoticcellrounding and spindle positioning". The Journal of Biological Chemistry. 286...
Ishihara O, Seki H, Tilly JL (February 2012). "Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women". Nature Medicine...
prognosis is: Mitotic rate: mitotic rate refers to the fraction of cells that are actively dividing within the tumor; GISTs that have a high mitotic rate have...
interphase of the mitoticcell cycle. Interphase is divided into three phases: Growth 1 (G1) phase: In this very active phase, the cell synthesizes its...
named because it has light blue blotches on its back that resemble cells undergoing mitotic division. Though not uncommon, it is found only in a small area...
meiosis primordial germ cells (PGCs) migrate to the gonads and mitotically divide along the genital ridge in clusters or nests of cells referred to as germline...
less commonly there can be anaplasia, mitotic activity, and necrosis.[citation needed] Some neuroendocrine tumor cells possess especially strong hormone receptors...
detect, as they may affect only a single cell - for instance, a post-mitotic neuron; improvements in single cell sequencing are therefore an important tool...
intercellular bridges connecting every cell in the cyst, called ring canals3. The four mitotic divisions result in cysts of 16 cells connected by 15 ring canals...
define the mitotic phase of an animal cell cycle—the division of the mother cell into two genetically identical daughter cells. The cell cycle is a vital...
grade of the tumor. The grade depends on how well the mast cells are differentiated, mitotic activity, location within the skin, invasiveness, and the...
Endoreduplication can be understood simply as a variant form of the mitoticcell cycle (G1-S-G2-M) in which mitosis is circumvented entirely, due to modulation...
within the testis will be initiated and start to divide mitotically, forming two types of A cells that contain an oval shaped nucleus with a nucleolus attached...
J. (2015). "Adherens junction remodeling during mitoticrounding of pseudostratified epithelial cells". Current Biology. 25 (1): 61–68. doi:10.1016/j...
to a mitoticcell cycle. It is an upstream regulator of the other G1 cyclins, and it is thought to be the key regulator linking cell growth to cell cycle...
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