For mastocytomas in dogs, see Mastocytoma in dogs.
Medical condition
Mastocytoma
Other names
Mast cell tumor
Mast cell tumor cytology
Specialty
Oncology
A mastocytoma or mast cell tumor is a type of round-cell tumor consisting of mast cells. It is found in humans and many animal species; it also can refer to an accumulation or nodule of mast cells that resembles a tumor.
Mast cells originate from the bone marrow and are normally found throughout the connective tissue of the body as normal components of the immune system. As they release histamine, they are associated with allergic reactions. Mast cells also respond to tissue trauma. Mast cell granules contain histamine, heparin, platelet-activating factor, and other substances. Disseminated mastocytosis is rarely seen in young dogs and cats, while mast cell tumors are usually skin tumors in older dogs and cats. Although not always malignant, they do have the potential to be. Up to 25 percent of skin tumors in dogs are mast cell tumors,[1] with a similar number in cats.[2]
^Brière C (2002). "Use of a reverse saphenous skin flap for the excision of a grade II mast cell tumor on the hind limb of a dog". Can Vet J. 43 (8): 620–2. PMC 339404. PMID 12170840.
^Johnson T, Schulman F, Lipscomb T, Yantis L (2002). "Histopathology and biologic behavior of pleomorphic cutaneous mast cell tumors in fifteen cats". Vet Pathol. 39 (4): 452–7. doi:10.1354/vp.39-4-452. PMID 12126148. S2CID 11717233.
A mastocytoma or mast cell tumor is a type of round-cell tumor consisting of mast cells. It is found in humans and many animal species; it also can refer...
A mastocytoma in dogs (or mast cell tumor in dogs) is a neoplasm (neoplasia) originating from mast cells in the domestic dog, which occurs mainly in the...
Extracutaneous mastocytoma presents with benign appearing mast cells occurring in sites other than the skin or bone marrow.: 617 Mastocytosis Skin lesion...
Solitary mastocytoma may be present at birth or may develop during the first weeks of life, originating as a brown macule that urticates on stroking.: 615 ...
inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. Together with masitinib (Kinavet (US)/Masivet (EU/ROW) by AB Science)...
expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more...
lesions Benign tumoral lesions Mastocytoma Abundant mast cells Tzanck smear test is useful for rapid diagnosis of mastocytoma in children Sebaceous hyperplasia...
Systemic mastocytosis was first reported by French scientists in 1936. Mastocytoma Horny HP, Sotlar K, Valent P (2007). "Mastocytosis: state of the art"...
nodes, and other organs by malignant histiocytes. A mast cell tumor (mastocytoma) is a type of tumor normally found in the skin of dogs. It can also invade...
pattern. Mast cell sarcoma should not be confused with extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases...
cell precursors. Mutations in c-Kit are associated with mastocytosis. Mastocytomas, or mast cell tumors, can secrete excessive quantities of degranulation...
tumor sometimes adheres strongly to surrounding muscles and tissues. Mastocytoma are the second most common skin tumor in cats. They are usually single...
work on the fundamental stages of HS/heparin biosynthesis using a mouse mastocytoma cell free system a lot is known about the order of enzyme reactions and...
training Hypoallergenic dog food List of dog diseases List of kennel clubs Mastocytoma in dogs Nematode infection in dogs Orthopedic Foundation for Animals...
injections of the virus, complete or partial remission of mast cell tumors (mastocytomas) was observed in dogs affected by this disease. Short-term remission...
poorly immunogenic Ag104A sarcoma and the extremely tumorigenic P815 mastocytoma provided the first systematic proof that anti-4-1BB antibodies have potent...
was focused on “Specific Suppressor Cells in Mice Bearing a Syngeneic Mastocytoma” Takei held a postdoctoral position in Microbiology at the University...
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