Global InformationFusome information
The fusome is a membranous structure found in the developing germ cell cysts of many insect orders.[1][2][3] Initial description of the fusome occurred in the 19th century and since then the fusome has been extensively studied in Drosophila melanogaster male and female germline development.[3] This structure has roles in maintaining germline cysts, coordinating the number of mitotic divisions prior to meiosis, and oocyte determination by serving as a structure for intercellular communication.[3][4][5]
- ^ Telfer, W. H. 1975. Development and physiology of the oocyte-nurse cell syncytium. Advances in insect physiology 11:223-319. DOI: 10.1016/S0065-2806(08)60164-2
- ^ Snapp, E. L., T. Iida, D. Frescas, J. Lippincott-Schwartz, and M. A. Lilly. (2004). The fusome mediates intercellular endoplasmic reticulum connectivity in Drosophila ovarian cysts. Mol Biol Cell 15: 4512-4521. doi/10.1091/mbc.E04 – 06 – 0475.
- ^ a b c Greenbaum, M. P., T. Iwarmori, G. M. Buchold, and M. M. Matzuk. (2011). Germ Cell Intercellular Bridges. Cold Spring Harb Perspect Biol 3:a005850 doi: 10.1101/cshperspect.a005850
- ^ de Cuevas, M., J. K. Lee, A. C. Spradling. (1996) α-spectrin is required for germline cell division and differentiation in the Drosophila ovary. Development 122: 3959-3968.
- ^ Lilly, M. A., M. de Cuevas, and A. C. Spradling. (2000). Cyclin A associates with the fusome during germline cyst formation in the Drosophila ovary. Developmental Biology 218: 53-63. doi:10.1006/dbio.1999.9570