Chemical compound
Methylergometrine Trade names Methergine Other names Methylergonovine; methylergobasin; Methylergobasine; Methylergobrevin; d -Lysergic acid 1-butanolamide; N -[(2S )-1-Hydroxybutan-2-yl]-6-methyl-9,10-didehydroergoline-8β-carboxamide AHFS/Drugs.com International Drug Names MedlinePlus a601077 Pregnancy category Routes of administration Oral ATC code Legal status
In general: ℞ (Prescription only)
Metabolism Liver Elimination half-life 30–120 minutes Excretion Mostly bile
(6aR ,9R )-N -[(2S )-1-hydroxybutan-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H -indolo[4,3-fg]quinoline-9-carboxamide
CAS Number 113-42-8 Y PubChem CID IUPHAR/BPS ChemSpider 7933 N UNII ChEMBL ChEMBL1201356 N CompTox Dashboard (EPA ) DTXSID1023283 ECHA InfoCard 100.003.661 Formula C 20 H 25 N 3 O 2 Molar mass 339.439 g·mol−1 3D model (JSmol) Melting point 172 °C (342 °F) Solubility in water Insoluble mg/mL (20 °C)
CC[C@@H](CO)NC(=O)[C@@H]2/C=C1/c3cccc4N\C=C(\C[C@H]1N(C)C2)c34
InChI=1S/C20H25N3O2/c1-3-14(11-24)22-20(25)13-7-16-15-5-4-6-17-19(15)12(9-21-17)8-18(16)23(2)10-13/h4-7,9,13-14,18,21,24H,3,8,10-11H2,1-2H3,(H,22,25)/t13-,14+,18-/m1/s1
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Methylergometrine , also known as methylergonovine and sold under the brand name Methergine , is a medication of the ergoline and lysergamide groups which is used as an oxytocic in obstetrics and in the treatment of migraine. It reportedly produces psychedelic effects similar to those of lysergic acid diethylamide (LSD) at high doses.[citation needed ]
It is on the World Health Organization's List of Essential Medicines.[1]
^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021) . Geneva: World Health Organization. hdl:10665/345533 . WHO/MHP/HPS/EML/2021.02.
Last Update: 2024-04-21T01:24:15Z
Methylergometrine , also known as methylergonovine and sold under the brand name Methergine, is a medication of the ergoline and lysergamide groups which...
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Last Update: 2024-04-05T11:46:39Z
metabolism into methylergometrine . Methysergide produces methylergometrine as a major active metabolite. Levels of methylergometrine are about 10-fold...
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Last Update: 2022-12-31T01:47:11Z
version. G02AB01 Methylergometrine G02AB02 Ergot alkaloids G02AB03 Ergometrine QG02AB53 Ergometrine, combinations G02AC01 Methylergometrine and oxytocin QG02AC90...
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Last Update: 2024-05-11T00:16:27Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 15730
Last Update: 2024-05-13T15:32:11Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
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Last Update: 2024-01-31T18:05:37Z
toxic ergoline derivatives are found in ergot-based drugs (such as methylergometrine , ergotamine or, previously, ergotoxine). The deleterious side effects...
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Last Update: 2024-05-12T13:50:35Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
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Last Update: 2024-02-26T08:01:45Z
of Sansert and Deseril; a prodrug which has to be metabolized to methylergometrine to become psychoactive Lysergic acid β-propanolamide†, also known...
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Last Update: 2024-05-06T04:44:40Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 13723
Last Update: 2024-04-26T06:08:05Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 1690
Last Update: 2024-05-10T01:52:24Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 10324
Last Update: 2024-05-11T15:01:13Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 10920
Last Update: 2024-05-07T15:05:37Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 2104
Last Update: 2024-04-11T07:06:59Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 9009
Last Update: 2024-04-29T21:57:26Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 11667
Last Update: 2024-05-13T19:16:59Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 7806
Last Update: 2024-05-01T19:04:30Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 8406
Last Update: 2024-05-11T21:46:15Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 5322
Last Update: 2024-05-06T17:49:48Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 5618
Last Update: 2024-05-14T00:37:17Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 3094
Last Update: 2024-05-08T15:18:49Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 4889
Last Update: 2023-12-19T21:21:39Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 1748
Last Update: 2024-05-14T06:10:24Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 8668
Last Update: 2024-05-13T05:57:32Z
bromocriptine, cabergoline, dihydroergotamine, ergotamine, lisuride, LSD, methylergometrine (methylergonovine), methysergide, pergolide) F-11,461 F-12826 F-13714...
Word Count : 3886
Last Update: 2024-05-07T03:36:15Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
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Last Update: 2024-03-23T05:22:42Z
breastfeeding at least 4 times per day anastrozole is an alternative Methylergometrine is an alternative Where permitted under national law and where culturally...
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Last Update: 2024-05-13T04:04:42Z
ETH-LAD IP-LAD LAE-32 LAMPA LPD-824 LSA LSD LSD-Pip LSH LSM-775 LSZ Methylergometrine MIPLA Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethyl‐ amines Piperazines...
Word Count : 6255