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Matrigel is the trade name for the solubilized basement membrane matrix secreted by Engelbreth-Holm-Swarm (EHS) mouse sarcoma cells produced by Corning Life Sciences. Matrigel resembles the laminin/collagen IV-rich basement membrane extracellular environment found in many tissues and is used by cell biologists as a substrate (basement membrane matrix) for culturing cells.[1][2]
^Hughes, C.S., Postovit, L.M., Lajoie, G.A. (2010). "Matrigel: a complex protein mixture required for optimal growth of cell culture". Proteomics. 10 (9): 1886–90. doi:10.1002/pmic.200900758. PMID 20162561.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^Benton, G., George, J., Kleinman, H.K., Arnaoutova, I. (2009). "Advancing science and technology via 3D culture on basement membrane matrix". Journal of Cellular Physiology. 221 (1): 18–25. doi:10.1002/jcp.21832. PMID 19492404.{{cite journal}}: CS1 maint: multiple names: authors list (link)
Matrigel is the trade name for the solubilized basement membrane matrix secreted by Engelbreth-Holm-Swarm (EHS) mouse sarcoma cells produced by Corning...
of Dental and Craniofacial Research from 1985 to 2006. She co-invented Matrigel. Kleinman received a B.S. in chemistry from Simmons College in 1969 and...
environment for cancer cells. Unlike other synthesized matrices such as matrigel which originated from mice sarcoma, myogel is extracted from a human benign...
plates should first be coated with an extracellular matrix (e.g. collagen, Matrigel) to promote hepatocyte attachment (typically within 1-3 hr after seeding)...
manufactured into a hydrogel by R&D Systems, a brand of Bio-Techne. Similar to Matrigel, this hydrogel is a natural extracellular matrix that mimics the complex...
synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel". Invest New Drugs. 23 (2): 121–2. doi:10.1007/s10637-005-5856-7. PMID 15744587...
Services Engelbreth-Holm-Swarm matrix, extracellular protein mixture known as Matrigel Early Harvest Scheme, a trade agreement Ecclesiastical History Society...
development of complex human tissue models. In 2013, using a 3-D scaffolding of Matrigel in various configurations, substantial pancreatic organoids was produced...
form a neuroectoderm. The neuroectoderm is then grown in a matrigel droplet. The matrigel provides nutrients and the neuroectoderm starts to proliferate...
The 3D medium can be made using an extracellular matrix hydrogel such as Matrigel or Cultrex BME, which is a laminin-rich extracellular matrix that is secreted...
Another approach resides in the use of hydrogels. Natural hydrogels such as Matrigel, collagen and fibrin have been used as entrapment matrices, wherein the...
antiangiogenic properties in prostate cancer cells (PCa). PCa was introduced onto a Matrigel and treated with tumstatin, and the formation of new blood vessels as seen...
migration, proliferation, and capacity to form capillary-like structures in Matrigel. GRCm38: Ensembl release 89: ENSMUSG00000041688 – Ensembl, May 2017 "Human...
Systems of placental organoids can also grow invasive EVT when cultured in Matrigel. Each of these options varies in their utility and accuracy to primary...
grow in vitro on scaffolds (biological or synthetic hydrogels such as Matrigel) or in a culture medium. Organoids are derived from three kinds of human...
cells and their derivatives by generating endothelial cell sprouts in Matrigel, all without the external introduction of vascular endothelial growth factor...
their phenotype better than cells cultured on other substrates such as matrigel or type 1 collagen. Though hydrogels do not yet have direct clinical relevance...
observed and substantiated on endothelial cells in the aortic ring, CAM, matrigel plug, and endothelial cell proliferation. In a normal pregnancy, CGB expression...
tissue" and the device gets its name from the fact that it is coated with Matrigel and nerve growth factor to encourage the expansion of neurites through...
polymers mimicking the cells natural environment or purified ECM such as matrigel, and any mixture of these three components. One such system has been developed...
the spheroids are generally embedded in an extracellular matrix, such as Matrigel, and transferred to a rotating bioreactor where different small molecules...
injecting them in the chest with a certain number of tumour cells and a Matrigel pre-formed extracellular matrix to hold the tumour cells together. The...
capable of forming new tips if provided with fresh mesenchyme or with a Matrigel artificially loaded with ramogens, such as GDNF and FGF1. The ramogens...
"Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase". Int. J. Cancer. 106 (3):...
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