For Organoids appearing in an anime series, see Zoids § Organoids.
Intestinal organoid grown from Lgr5+ stem cells
An organoid is a miniaturised and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural, and biological complexity of that organ.[1] It is derived from one or a few cells from a tissue, embryonic stem cells, or induced pluripotent stem cells, which can self-organize in three-dimensional culture owing to their self-renewal and differentiation capacities. The technique for growing organoids has rapidly improved since the early 2010s, and The Scientist named it one of the biggest scientific advancements of 2013.[2] Scientists and engineers use organoids to study development and disease in the laboratory, for drug discovery, development in industry,[3] personalized diagnostics and medicine, gene and cell therapies, tissue engineering, and regenerative medicine.
^Zhao Z, Chen X, Dowbaj AM, Sljukic A, Bratlie K, Lin L, Fong ELS, Balachander GM, Chen Z, Soragni A, Huch M, Zeng YA, Wang Q, Yu H. Organoids. Nature Reviews Methods Primers 2, 94 (2022). https://doi.org/10.1038/s43586-022-00174-y
^Grens K (December 24, 2013). "2013's Big Advances in Science". The Scientist. Retrieved 26 December 2013.
^Hans Clevers, Asher Mullard. Mini-organs attract big pharma. Nature Reviews Drug Discovery (16 February 2023). https://doi.org/10.1038/d41573-023-00030-y
An organoid is a miniaturised and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural, and...
neural, or brain organoid, describes an artificially grown, in vitro, tissue resembling parts of the human brain. Neural organoids are created by culturing...
Organoid intelligence (OI) is an emerging field of study in computer science and biology that develops and studies biological computing using 3D cultures...
A myelinoid or myelin organoid is a three dimensional in vitro cultured model derived from human pluripotent stem cells (hPSCs) that represents various...
creation of three-dimensional (3D) organ-like architectures known as "organoids," which are able to exhibit properties of their corresponding real organs...
well as diseases associated with it. They are a model system an embryonic organoid for the study of mammalian development (including humans) and disease....
Latin name, the second term is its name in English; also known as an "organoid nevus": 661 and "nevus sebaceus of Jadassohn": 773 ) is a congenital,...
Finally, using 3D embryoid body- and organoid-based techniques, small aggregates of mouse ESCs (Embryonic Organoids, or Gastruloids) are able to show a...
biology to further understand stem cell niches, and to generate intestinal organoids. The crypts of Lieberkühn are named after the eighteenth-century German...
An assembloid is an in vitro model that combines two or more organoids, spheroids, or cultured cell types to recapitulate structural and functional properties...
and distal airway epithelia. After being developed in 3D cultures, the organoids were separated into individual cells to form 2D monolayers. These lung...
vivo patient derived xenograft (PDX), cell line derived xenograft (CDX), organoids and 3D models, as well as oncology databases, biomarker, bioanalysis and...
processing and integrating big data. This is particularly important for organoid and tissue engineering development which use microscopy imaging as a key...
has been shown to increase markers of neuroplasticity in human brain organoids and improve memory performance in human subjects. LSD may have analgesic...
microbiology Institute of Molecular and Cell Biology (disambiguation) Meiomitosis Organoid Outline of cell biology Alberts, Bruce; Johnson, Alexander D.; Morgan,...
Scientists coalesce recent developments using human brain organoids into a new field they term organoid intelligence (OI), seeking to harness OI for computing...
organism. The organogenesis process can be studied using embryos and organoids. The endoderm is the inner most germ layer of the embryo which gives rise...
the inflammation caused that leads to the associated diseases. Gastric organoids can be used as a model for the study of H. pylori pathogenesis. List of...
Cultrex BME is commonly used for the culture of pluripotent stem cells and organoids.[citation needed] Cultrex BME is gelatinous at 4 °C. The matrix proteins...
adult stem cells, creating organoids of the small intestine. Clevers's group has applied this technology to culturing organoids from other organs, such as...
functional repair in culture of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Bacteriophage therapy (phage therapy) is...
Japanese cruiser Ōi O-I, a Japanese tank design of the Second World War Organoid intelligence, a field of study related to computer science and biology...
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