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Latrophilin 3 information


ADGRL3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesADGRL3, CIRL3, LEC3, CL3, LPHN3, adhesion G protein-coupled receptor L3
External IDsOMIM: 616417; MGI: 2441950; HomoloGene: 22878; GeneCards: ADGRL3; OMA:ADGRL3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 4: 61.2 – 62.08 MbChr 5: 81.02 – 81.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Latrophilin 3 is a protein that in humans is encoded by the ADGRL3 gene.[5][6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000150471 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037605 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hayflick JS (Jan 2001). "A family of heptahelical receptors with adhesion-like domains: a marriage between two super families". Journal of Receptor and Signal Transduction Research. 20 (2–3): 119–31. doi:10.3109/10799890009150640. PMID 10994649. S2CID 19919738.
  6. ^ "Entrez Gene: LPHN3 latrophilin 3".

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Latrophilin 3

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Latrophilin

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attention-deficit hyperactivity disorder and cancer. Latrophilin 1 (LPHN1) Latrophilin 2 (LPHN2) Latrophilin 3 (LPHN3) ELTD1 Kreienkamp HJ, Soltau M, Richter...

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Attention deficit hyperactivity disorder

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GRIN2A, ADRA2A, TPH2, and BDNF. A common variant of a gene called latrophilin 3 is estimated to be responsible for about 9% of cases and when this variant...

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Latrophilin 2

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Latrophilin 2 is a protein that in humans is encoded by the ADGRL2 gene. This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors...

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Latrophilin 1

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Latrophilin 1 is a protein that in humans is encoded by the ADGRL1 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized...

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Latrotoxin

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α-LTX in its tetrameric form interacts with receptors (neurexins and latrophilins) on the neuronal membrane, which causes insertion of α-LTX into the membrane...

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Emodepside

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be through binding to a group of G-protein coupled receptors called latrophilins, first identified as being target proteins for α-latrotoxin (the other...

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Donepezil

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Galactose binding lectin domain

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the following proteins: Plant beta-galactosidases EC 3.2.1.23 (lactases). Mammalian latrophilin, the calcium independent receptor of alpha-latrotoxin...

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Botulinum toxin

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toxin in food. The estimated human median lethal dose of type A toxin is 1.3–2.1 ng/kg intravenously or intramuscularly, 10–13 ng/kg when inhaled, or 1000 ng/kg...

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Physostigmine

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nicotinic and muscarinic acetylcholine receptors. Physostigmine has an LD50 of 3 mg/kg in mice. Physostigmine functions as an acetylcholinesterase inhibitor...

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Anticholinergic

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Neurexin

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indicates that neuroexophilins have a functional role in certain circuits. Latrophilins are adhesion G protein-coupled receptors that reside on the postsynaptic...

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biosynthesis is not enough to meet human requirements. In the hepatic PEMT route, 3-phosphoglycerate (3PG) receives 2 acyl groups from acyl-CoA forming a phosphatidic...

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ancestral receptor. In fact, relatively minor mutations, such as a change in 3 amino acids in many of these receptors can convert a cation-selective channel...

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Residue Reviews. Vol. 231. pp. 119–162. doi:10.1007/978-3-319-03865-0_5. ISBN 978-3-319-03864-3. PMID 24723135. {{cite book}}: |journal= ignored (help)...

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absorbed, with a bioavailability of about 40% in the 3-mg dose. Pharmacokinetics are linear up to 3 mg BID, but nonlinear at higher doses. Elimination is...

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Itopride

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Metabolism in Drug Design (3rd ed.). Weinheim: Wiley-VCH. p. 132. ISBN 978-3-527-32954-0. Iwanaga Y, Miyashita N, Saito T, Morikawa K, Itoh Z (June 1996)...

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Neostigmine

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7.7, 7.4, 7.4, 3.8, and 3.1 parts per million. The higher shifts are due to the aromatic hydrogens. The lower shifts at 3.8 ppm and 3.1 ppm are due to...

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