LMO4 information

LMO4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2L4Z
Identifiers
Aliases	LMO4, LIM domain only 4
External IDs	OMIM: 603129 MGI: 109360 HomoloGene: 4927 GeneCards: LMO4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	87,348,923 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	143,910,981 bp
RNA expression pattern
	Top expressed in
	dorsolateral prefrontal cortex; ; prefrontal cortex; ; Brodmann area 46; ; superior frontal gyrus; ; parietal lobe; ; postcentral gyrus; ; Brodmann area 9; ; frontal pole; ; cingulate gyrus; ; Brodmann area 10;
	Top expressed in
	cingulate gyrus; ; superior frontal gyrus; ; visual cortex; ; primary motor cortex; ; corneal stroma; ; lacrimal gland; ; olfactory tubercle; ; entorhinal cortex; ; eyelid; ; prefrontal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; metal ion binding; protein binding; cis-regulatory region sequence-specific DNA binding; transcription factor binding;
Cellular component	transcription regulator complex; cell leading edge;
Biological process	regulation of transcription, DNA-templated; ventricular septum development; spinal cord association neuron differentiation; thymus development; negative regulation of protein-containing complex assembly; transcription, DNA-templated; ventral spinal cord interneuron differentiation; regulation of cell activation; spinal cord motor neuron differentiation; regulation of cell fate specification; positive regulation of transcription by RNA polymerase II; neural tube closure; transcription by RNA polymerase II; positive regulation of kinase activity; regulation of cell migration;
	Sources:Amigo / QuickGO
Orthologs
	8543
	16911
	ENSG00000143013
	ENSMUSG00000028266
	P61968
	P61969
	NM_006769; NM_001369491
	NM_001161769; NM_001161770; NM_010723
	NP_006760; NP_001356420
	NP_001155241; NP_001155242; NP_034853
	Wikidata
View/Edit Human	View/Edit Mouse

LIM domain transcription factor LMO4 is a protein that in humans is encoded by the LMO4 gene.^[5]

LIM domain only 4 is a cysteine-rich, two LIM domain-containing protein that may play a role as a transcriptional regulator or possibly an oncogene. Its mRNA is characterized by a GC-rich 5' region and by multiple ATTT motifs in the 3' region. A variant transcript missing a portion of the 5' region has been identified but cannot be confirmed because of the GC-rich nature of the region.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143013 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028266 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: LMO4 LIM domain only 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143013 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028266 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: LMO4 LIM domain only 4".

LMO4 information

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