positive regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4807
18071
Ensembl
ENSG00000171786
ENSMUSG00000051251
UniProt
Q02575 Q5T203
Q02576
RefSeq (mRNA)
NM_005598
NM_010916
RefSeq (protein)
NP_005589 NP_005589.1
NP_035046
Location (UCSC)
Chr 1: 160.37 – 160.37 Mb
Chr 1: 171.88 – 171.89 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene.[5]
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM][5]
^ abcGRCh38: Ensembl release 89: ENSG00000171786 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000051251 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene. The helix-loop-helix (HLH) proteins are a family of putative transcription...