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Intermediate progenitor cell information


Intermediate progenitor cells (IPCs) are a type of progenitor cell in the developing cerebral cortex. They are multipolar cells produced by radial glial cells who have undergone asymmetric division. IPCs can produce neuron cells via neurogenesis and are responsible for ensuring the proper quantity of cortical neurons are produced.[1][2] In mammals, neural stem cells are the primary progenitors during embryogenesis whereas intermediate progenitor cells are the secondary progenitors.

  1. ^ Kowalczyk, Tom; Pontious, Adria; Englund, Chris; Daza, Ray A. M.; Bedogni, Francesco; Hodge, Rebecca; Attardo, Alessio; Bell, Chris; Huttner, Wieland B. (2009-10-01). "Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex". Cerebral Cortex. 19 (10): 2439–2450. doi:10.1093/cercor/bhn260. ISSN 1047-3211. PMC 2742596. PMID 19168665.
  2. ^ Harris, Lachlan; Zalucki, Oressia; Gobius, Ilan; McDonald, Hannah; Osinki, Jason; Harvey, Tracey J.; Essebier, Alexandra; Vidovic, Diana; Gladwyn-Ng, Ivan; Burne, Thomas H.; Heng, Julian I.; Richards, Linda J.; Gronostajski, Richard M.; Piper, Michael (2016-10-28). "Transcriptional Regulation of Intermediate Progenitor Cell Generation during Hippocampal Development". Development. 143: 4620–4630. doi:10.1242/dev.140681.

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Intermediate progenitor cell

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Intermediate progenitor cells (IPCs) are a type of progenitor cell in the developing cerebral cortex. They are multipolar cells produced by radial glial...

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Progenitor cell

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A progenitor cell is a biological cell that can differentiate into a specific cell type. Stem cells and progenitor cells have this ability in common. However...

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Neuroepithelial cell

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Neuroepithelial cells are the stem cells of the central nervous system, known as neural stem cells, and generate the intermediate progenitor cells known as radial...

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Precursor cell

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In cell biology, precursor cells—also called blast cells—are partially differentiated, or intermediate, and are sometimes referred to as progenitor cells...

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Oligodendrocyte progenitor cell

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Oligodendrocyte progenitor cells (OPCs), also known as oligodendrocyte precursor cells, NG2-glia, O2A cells, or polydendrocytes, are a subtype of glia...

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Radial glial cell

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Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons...

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Endothelial stem cell

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progenitor cells, which are intermediate stem cells that lose potency. Progenitor stem cells are committed to differentiating along a particular cell...

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Neural stem cell

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Neural stem cells (NSCs) are self-renewing, multipotent cells that firstly generate the radial glial progenitor cells that generate the neurons and glia...

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Embryomics

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temporary cells are called progenitor cells, and are intermediate cell types which disappear during embryogenesis by turning into other progenitor cells, or...

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Thymic epithelial cell

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represent one of immature progenitors cells - cTEC committed progenitors. These cells are also called thymic epithelial progenitors cells (TEPCs) and they provide...

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T cell

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The newly arrived CLP cells are CD4−CD8−CD44+CD25−ckit+ cells, and are termed early thymic progenitor (ETP) cells. These cells will then undergo a round...

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Neuroblast

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Drosophila, neuroblasts are neural progenitor cells which divide asymmetrically to produce a neuroblast, and a daughter cell of varying potency depending on...

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Lymphopoiesis

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2008 p.702-703 The Common Myelolymphoid Progenitor: A Key Intermediate Stage in Hemopoiesis Generating T and B Cells; Min Lu, Hiroshi Kawamoto, Yoshihiro...

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Airway basal cell

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basal cells are found deep in the respiratory epithelium, attached to, and lining the basement membrane. Basal cells are the stem cells or progenitors of...

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Eomesodermin

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the intermediate progenitor stage of the developing neuron. Neurons, the primary functional cells of the brain, are developed from radial glia cells. This...

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Intermediate filament

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Intermediate filaments (IFs) are cytoskeletal structural components found in the cells of vertebrates, and many invertebrates. Homologues of the IF protein...

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List of human cell types derived from the germ layers

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myeloid cells Endothelial progenitor cell Endothelial colony forming cell Endothelial stem cell Angioblast/Mesoangioblast Pericyte Mural cell Mesothelial...

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Natural killer cell

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innate lymphoid progenitor, which is downstream of the common lymphoid progenitor from which B and T lymphocytes are also derived. NK cells are known to...

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Transdifferentiation

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mature somatic cell is transformed into another mature somatic cell without undergoing an intermediate pluripotent state or progenitor cell type. It is a...

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NFIX

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shown to interact with STAT3. In embryonic cells, Nfix has been shown to regulate intermediate progenitor cell (IPC) generation by promoting the transcription...

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Photoreceptor cell

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photoreceptors: proliferation of multi-potent retinal progenitor cells (RPCs); restriction of competence of RPCs; cell fate specification; photoreceptor gene expression;...

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Mast cell

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in detail by Heneberg, claiming that mast cells may be inadvertently included in the stem or progenitor cell isolates, since part of them is positive for...

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Neurogenesis

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Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular...

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Keratinocyte

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partly because stem/progenitor cells fail to self-renew or differentiate. DNA damage caused by exposure of stem/progenitor cells to reactive oxygen species...

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Osteoblast

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skull and others. During osteoblast differentiation, the developing progenitor cells express the regulatory transcription factor Cbfa1/Runx2. A second required...

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Ductal cells

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and exocrine cells originate in the pancreatic ducts as progenitor cells. In adult ductal cells, there are observations that these cells take on the identity...

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Development of the cerebral cortex

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embryonic stem cells (ESC). By carefully using embryo body intermediates and cultured in a serum free environment cortical progenitors form in a space...

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TBR1

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downregulated and Tbr2 is expressed as the cell differentiates into an intermediate progenitor cell. Likewise, in the final step, Tbr2 is extremely downregulated...

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Mesoderm

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(August 2009). "Human embryonic stem cell-derived mesoderm-like epithelium transitions to mesenchymal progenitor cells". Tissue Engineering. Part A. 15 (8):...

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