This article's tone or style may not reflect the encyclopedic tone used on Wikipedia. See Wikipedia's guide to writing better articles for suggestions.(November 2021) (Learn how and when to remove this message)
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cells (WBCs).[1] It is more formally known as lymphoid hematopoiesis.
Disruption in lymphopoiesis can lead to a number of lymphoproliferative disorders, such as lymphomas and lymphoid leukemias.
Lymphopoiesis Glossary
• antigen any molecule that can provoke an immune defense
• B cells lymphocytes that ultimately produce antibodies
• bone marrow the center of bones capable of producing all red and white blood cells in the adult
• cortex the outer portion of any organ
• cytoplasm the portion of a cell between the nucleus and the membrane
• differentiation permanent changes to a cell developing over time and with cell division
• granules grains found in many white blood cells, composed of defensive chemicals
• hematopoietic that which gives rise to any blood cell type
• lineage a type of cell and its descendants by division and differentiation
• lymphocytes a special 'lineage' of WBC
• macrophages myeloid descendants (some may be lymphoid) with 'eating' abilities, also cooperate with lymphocytes
• myeloid ancestors of WBCs with granules and also of macrophages
• T Cells "management" lymphocytes for immunity
• (WBC) White Blood Cell in contrast to the much more common Red Blood Cell; responsible for defense
edit
^Birbrair, Alexander; Frenette, Paul S. (2016-03-01). "Niche heterogeneity in the bone marrow". Annals of the New York Academy of Sciences. 1370 (1): 82–96. Bibcode:2016NYASA1370...82B. doi:10.1111/nyas.13016. ISSN 1749-6632. PMC 4938003. PMID 27015419.
gestation, the developing embryo has begun its own lymphopoiesis from the fetal liver. Lymphopoiesis also arises from the yolk sac. This is in contrast...
rise to B cells and T cells. Those cells' differentiation (that is, lymphopoiesis) is not complete until they migrate to lymphatic organs such as the...
(megakaryocytes), and the two main groups of WBCs, myelocytes and lymphocytes. Lymphopoiesis Myelopoiesis Leukopoiesis at the U.S. National Library of Medicine Medical...
in a more plastic fashion. The formation of lymphocytes is known as lymphopoiesis. In mammals, B cells mature in the bone marrow, which is at the core...
is composed of T-cells, B-cells, and natural killer cells. This is lymphopoiesis. Cells of the myeloid lineage, which include granulocytes, megakaryocytes...
tissue mostly replacing the thymic stroma. However, residual T cell lymphopoiesis continues throughout adult life, providing some immune response. The...
lineage is composed of T-cells, B-cells and natural killer cells. This is lymphopoiesis. Cells of the myeloid lineage, which include granulocytes, megakaryocytes...
from The Collection B-NK (Progenitor for B and NK), a term related to lymphopoiesis BNK, Busan Bank BNK48, an idol group based in Bangkok, Thailand This...
development until terminal differentiation into plasma cells. During B cell lymphopoiesis, CD19 surface expression starts during immunoglobulin (Ig) gene rearrangement...
"Expression of CD28 by Bone Marrow Stromal Cells and Its Involvement in B Lymphopoiesis". The Journal of Immunology. 169 (5): 2292–2302. doi:10.4049/jimmunol...
maintenance and cell lineage determination, such as osteogenesis, myogenesis, lymphopoiesis and hematopoiesis. It can also be associated with mutations in the histone...
inducing B cell apoptosis (cell death) and the degradation of B cell lymphopoiesis. They are also able to induce suppressor molecules that can inhibit...
inflammation. LNK has been found to function as a negative regulator in lymphopoiesis, megakaryopoiesis, erythropoiesis as well as HSC expansion by moderating...
Schroeder HW (June 1996). "The J chain gene is transcribed during B and T lymphopoiesis in humans". Journal of Immunology. 156 (11): 4240–4244. doi:10.4049/jimmunol...
KL, Garrett KP, Comp PC, Schipul AH, Kincade PW (January 2003). "B lymphopoiesis is active throughout human life, but there are developmental age-related...
Beutler, Bruce (May 2011). "The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow". Nature Immunology. 12 (5): 434–440. doi:10.1038/ni...
integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis". Blood. 115 (12): 2380–2390. doi:10.1182/blood-2009-07-233031. PMC 2845896...
S2CID 1843716. Cambier J (June 2005). "Immunosenescence: a problem of lymphopoiesis, homeostasis, microenvironment, and signaling". Immunological Reviews...
(class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for the B and T lymphocyte development...
Global Information