antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
blood vessel development
negative regulation of entry of bacterium into host cell
integrin-mediated signaling pathway
calcium ion transmembrane transport
negative regulation of macrophage derived foam cell differentiation
negative regulation of extrinsic apoptotic signaling pathway
leukocyte migration
cell-substrate adhesion
negative regulation of lipoprotein metabolic process
negative regulation of lipid transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of cell adhesion
ERK1 and ERK2 cascade
cell growth
positive regulation of osteoblast proliferation
cell adhesion
angiogenesis
vasculogenesis
cellular calcium ion homeostasis
positive regulation of cytosolic calcium ion concentration
positive regulation of cell population proliferation
cell migration
neutrophil degranulation
positive regulation of MAPK cascade
cell adhesion mediated by integrin
viral entry into host cell
regulation of transforming growth factor beta activation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
3685
16410
Ensembl
ENSG00000138448
ENSMUSG00000027087
UniProt
P06756
P43406
RefSeq (mRNA)
NM_001144999 NM_001145000 NM_002210
NM_008402 NM_001398691
RefSeq (protein)
NP_001138471 NP_001138472 NP_002201
NP_032428 NP_001385620
Location (UCSC)
Chr 2: 186.59 – 186.68 Mb
Chr 2: 83.55 – 83.64 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000138448 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000027087 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, Kaos FT, Schwartz E, Phillips D, Bennett JS (June 1988). "Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa". The Journal of Clinical Investigation. 81 (6): 1993–8. doi:10.1172/JCI113548. PMC 442653. PMID 2454952.
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