Integrin alpha D information

ITGAD
Identifiers
Aliases	ITGAD, ADB2, CD11D, integrin subunit alpha D
External IDs	OMIM: 602453; MGI: 3578624; HomoloGene: 56919; GeneCards: ITGAD; OMA:ITGAD - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	31,426,505 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,822,988 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; spleen; ; gastrocnemius muscle; ; lymph node; ; muscle of thigh; ; appendix; ; blood; ; decidua; ; right lobe of liver; ; gallbladder;
	Top expressed in
	spleen; ; spermatid; ; testicle; ; spermatocyte; ; islet of Langerhans; ; bone marrow; ; embryo; ; granulocyte; ; thymus; ; primary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein heterodimerization activity;
Cellular component	integral component of membrane; cell surface; integrin complex; plasma membrane; membrane;
Biological process	integrin-mediated signaling pathway; heterotypic cell-cell adhesion; extracellular matrix organization; cell adhesion; immune response;
	Sources:Amigo / QuickGO
Orthologs
	3681
	381924
	ENSG00000156886
	ENSMUSG00000070369
	Q13349
	Q3V0T4
	NM_005353; NM_001318185
	NM_001029872; NM_001177632
	NP_001305114; NP_005344
	NP_001025043
	Wikidata
View/Edit Human	View/Edit Mouse

Integrin alpha-D is a protein that in humans is encoded by the ITGAD gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156886 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070369 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wong DA, Davis EM, LeBeau M, Springer TA (Aug 1996). "Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit". Gene. 171 (2): 291–4. doi:10.1016/0378-1119(95)00869-1. PMID 8666289.
^ Shelley CS, Da Silva N, Georgakis A, Chomienne C, Arnaout MA (Aug 1998). "Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb". Genomics. 49 (2): 334–6. doi:10.1006/geno.1998.5232. PMID 9598326.
^ "Entrez Gene: ITGAD integrin, alpha D".

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