Alpha-7 integrin is a protein that in humans is encoded by the ITGA7 gene.[5][6] Alpha-7 integrin is critical for modulating cell-matrix interactions. Alpha-7 integrin is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. Mutations in ITGA7 have been associated with congenital myopathies and noncompaction cardiomyopathy, and altered expression levels of alpha-7 integrin have been identified in various forms of muscular dystrophy.
^ abcGRCh38: Ensembl release 89: ENSG00000135424 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000025348 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Wang W, Wu W, Desai T, Ward DC, Kaufman SJ (Aug 1995). "Localization of the alpha 7 integrin gene (ITGA7) on human chromosome 12q13: clustering of integrin and Hox genes implies parallel evolution of these gene families". Genomics. 26 (3): 568–70. doi:10.1016/0888-7543(95)80176-M. PMID 7607681.
Alpha-7integrin is a protein that in humans is encoded by the ITGA7 gene. Alpha-7integrin is critical for modulating cell-matrix interactions. Alpha-7...
Integrinalpha M (ITGAM) is one protein subunit that forms heterodimeric integrinalpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)...
is an integrinalpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrinalpha chain family...
Integrinalpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrinalpha chain 2b. Integrins are...
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans...
known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c . CD11c is an integrinalpha X chain protein...
Integrins are transmembrane receptors that help cell-cell and cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal...
Integrinalpha-5 is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrinalpha chain family. Integrins...
Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin...
with integrinalpha 1 and integrinalpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrinalpha 3 to...
Integrinalpha-9 is a protein that in humans is encoded by the ITGA9 gene. Cytogenetic location: 3p22.2 This gene encodes an alphaintegrin. Integrins...
CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one of a number of alpha chains...
Integrinalpha-8 is a protein that in humans is encoded by the ITGA8 gene. GRCh38: Ensembl release 89: ENSG00000077943 – Ensembl, May 2017 GRCm38: Ensembl...
Integrinalpha-D is a protein that in humans is encoded by the ITGAD gene. GRCh38: Ensembl release 89: ENSG00000156886 – Ensembl, May 2017 GRCm38: Ensembl...
receptor, the fibrinogen alpha chain, the integrinalpha chain, Hemoglobin, alpha 1 It should be distinguished from the term alpha helix, which refers to...
Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. CD103...
to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrinalpha-4 and Integrin beta-7), blocking the α4β7 integrin results...
Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta subunits...
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins...
PAK4. ITGB5 encodes a subunit of integrin that can interact with several alpha chains to form a variety of integrin heterodimers. It also plays a potential...
survival, and transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits...
This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular...
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