Human adenovirus 41(HAdV-F41), is an enteric Adenovirus, a nonenveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome.[1]
It can particularly target the gastrointestinal tract to cause gastroenteritis, with symptoms similar to rotavirus gastroenteritis and norovirus.[2] It may be present in the gut without causing symptoms and can be detected by using molecular based assays and enzyme immunoassay.[2][3]
As of August 2022, human adenovirus 41 has been identified in a majority of small children with hepatitis of unknown cause in 2 case series.
^Gallardo, José; Pérez-Illana, Marta; Martín-González, Natalia; San Martín, Carmen (15 May 2021). "Adenovirus Structure: What Is New?". International Journal of Molecular Sciences. 22 (10): 5240. doi:10.3390/ijms22105240. ISSN 1422-0067. PMC 8156859. PMID 34063479.
^ abCrews, Jonathan D. (2018). "12. Healthcare-associated gastrointestinal infections". In McNeil, J. Chase; Campbell, Judith R.; Crews, Jonathan D. (eds.). Healthcare-Associated Infections in Children: A Guide to Prevention and Management. Springer. p. 202. ISBN 978-3-319-98121-5.
^"11.2. Viral pathogens". Guidelines for drinking-water quality: fourth edition incorporating the first and second addenda (4th ed.). World Health Organization. 2022. p. 276. ISBN 978-92-4-004506-4.
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