A helper dependent virus, also termed a gutless virus, is a synthetic viral vector dependent on the assistance of a helper virus in order to replicate,[1] and can be used for purposes such as gene therapy. Naturally-occurring satellite viruses are also helper virus dependent, and can sometimes be modified to become viral vectors.
helpervirus is a virus that allows an otherwise-deficient coinfecting virus to replicate. These can be naturally occurring as with Hepatitis D virus...
The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune...
cells. AAVs, however, require the presence of a "helpervirus" such as an adenovirus or herpes simplex virus to replicate within the host, although it can...
their helperviruses; while they are sometimes considered to be genomic elements of their helperviruses, they are not always found within their helper viruses...
infected by a certain helpervirus; Sputnik uses the helpervirus's machinery for reproduction and inhibits replication of the helpervirus. It is known as...
SV40 based vectors as a viral vector for gene therapy. In these helperdependentvirus or packaging cell line assisted produced vectors the SV40 large...
cyclin dependent kinases attach to cyclin signaling the cell further into interphase. At the peak of the cyclin, attached to the cyclin dependent kinases...
for DNA synthesis are recognized: All cellular life forms and many DNA viruses, phages and plasmids use a primase to synthesize a short RNA primer with...
group-specific antigen helical helperdependentvirushelpervirus Any virus which aids or allows the replication of a coinfecting virus that is incapable of replicating...
of virology engaged in the study and engineering of synthetic man-made viruses. It is a multidisciplinary research field at the intersection of virology...
Mimivirus-dependentvirus Zamilon, or Zamilon, is a virophage, a group of small DNA viruses that infect protists and require a helpervirus to replicate;...
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals...
Virusoids are essentially viroids that have been encapsulated by a helpervirus coat protein. They are thus similar to viroids in their means of replication...
Respiratory syncytial virus (RSV), also called human respiratory syncytial virus (hRSV) and human orthopneumovirus, is a contagious virus that causes infections...
is a realm of viruses that includes all viruses that use a homologous RNA-dependent polymerase for replication. It includes RNA viruses that encode an...
Norovirus, also known as Norwalk virus and sometimes referred to as the winter vomiting disease, is the most common cause of gastroenteritis. Infection...
together to form immature viruses. Like the other steps, how a particular virus is assembled is dependent on what type of virus it is. Assembly can occur...
domain facilitates ORC association with chromosomes and Epstein-Barr virus origin-dependent replication. Therefore, it is intriguing to speculate that both...
to positive-sense RNA by an RNA-dependent RNA polymerase before translation. Purified RNA of a positive-sense virus can directly cause infection though...
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