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HUGO Gene Nomenclature Committee information


HGNC
Content
DescriptionHGNC is responsible for approving unique symbols and names for human loci, including protein coding genes, RNA genes and pseudogenes, to allow unambiguous scientific communication.
Data types
captured
Gene nomenclature
OrganismsHuman
Contact
Research centerEMBL-EBI, UK;
Primary citationBraschi et al. (2019)[1]
Access
Websitewww.genenames.org
www.genenames.org/news
Download URLStatistics & Downloads
Custom Downloads
HGNC Biomart
Web service URLrest.genenames.org
Tools
WebHGNC Comparison of Orthology Predictions,[2][3] Search
Miscellaneous
Curation policyYes

The HUGO Gene Nomenclature Committee (HGNC) is a committee of the Human Genome Organisation (HUGO) that sets the standards for human gene nomenclature. The HGNC approves a unique and meaningful name for every known human gene,[4][5] based on a query of experts. In addition to the name, which is usually 1 to 10 words long, the HGNC also assigns a symbol (a short group of characters) to every gene. As with an SI symbol, a gene symbol is like an abbreviation but is more than that, being a second unique name that can stand on its own just as much as substitute for the longer name. It may not necessarily "stand for" the initials of the name, although many gene symbols do reflect that origin.

  1. ^ Braschi B, Denny P, Gray K, Jones T, Seal R, Tweedie S, et al. (January 2019). "Genenames.org: the HGNC and VGNC resources in 2019". Nucleic Acids Research. 47 (D1): D786–D792. doi:10.1093/nar/gky930. PMC 6324057. PMID 30304474.
  2. ^ Wright MW, Eyre TA, Lush MJ, Povey S, Bruford EA (November 2005). "HCOP: the HGNC comparison of orthology predictions search tool". Mammalian Genome. 16 (11): 827–8. doi:10.1007/s00335-005-0103-2. PMID 16284797. S2CID 1091618.
  3. ^ Eyre TA, Wright MW, Lush MJ, Bruford EA (January 2007). "HCOP: a searchable database of human orthology predictions". Briefings in Bioinformatics. 8 (1): 2–5. doi:10.1093/bib/bbl030. PMID 16951416.
  4. ^ "About the HGNC | HUGO Gene Nomenclature Committee".
  5. ^ Bruford, Elspeth A.; Braschi, Bryony; Denny, Paul; Jones, Tamsin E. M.; Seal, Ruth L.; Tweedie, Susan (August 2020). "Guidelines for human gene nomenclature". Nature Genetics. 52 (8): 754–758. doi:10.1038/s41588-020-0669-3. PMC 7494048. PMID 32747822.

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HUGO Gene Nomenclature Committee

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The HUGO Gene Nomenclature Committee (HGNC) is a committee of the Human Genome Organisation (HUGO) that sets the standards for human gene nomenclature. The...

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Gene nomenclature

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associated with protein nomenclature, as genes and the proteins they code for usually have similar nomenclature. An international committee published recommendations...

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Human Genome Organisation

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Human Genome Project. HUGO has four active committees, including the HUGO Gene Nomenclature Committee (HGNC), and the HUGO Committee on Ethics, Law and Society...

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Gene family

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techniques to detect gene families that are under the effect of natural selection. The HUGO Gene Nomenclature Committee (HGNC) creates nomenclature schemes using...

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Pseudoautosomal region

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"Pseudoautosomal region 2 (PAR2) Gene group". HUGO Gene Nomenclature Committee. Retrieved 2019-08-30. "WASH6P". HUGO Gene Nomenclature Committee. Retrieved 2019-08-30...

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Hugo

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unincorporated community HUGO (cable system), a submarine telecommunications cable Human Genome Organization HUGO Gene Nomenclature Committee (HGNC), often (incorrectly)...

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GeneCards

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and NCBI. The core gene list is based on NCBI, Ensembl and approved gene symbols published by the HUGO Gene Nomenclature Committee (HGNC). The information...

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AAA proteins

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PMID 20130675. "Gene group: AAA ATPases (ATAD)". HUGO Gene Nomenclature Committee. "Gene group: Torsins (TOR)". HUGO Gene Nomenclature Committee. "Symbol report...

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Gene Wiki

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for the Gene Wiki project are created by a bot and contain links to the following primary gene/protein databases: HUGO Gene Nomenclature Committee – official...

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Solute carrier family

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in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the basis for the...

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DNA methyltransferase

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045112.117. PMC 5473107. PMID 28620075. "DNMT1". Gene Symbol Report. HUGO Gene Nomenclature Committee. Archived from the original on 2012-10-06. Retrieved...

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FKBP

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PMID 20353181. "Gene group: FKBP prolyl isomerases (FKBP)". HUGO Gene Nomenclature Committee. "Symbol report for FKBP1C". HUGO Gene Nomenclature Committee. Anti-rejection...

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Chromosome 21

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Human Cytogenetic Nomenclature (2013). Arbitrary unit. gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region...

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Gene

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relatively constant level. Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC), a committee of the Human Genome Organisation...

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X chromosome

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- Gene". NCBI. CCDS Release 20 for Homo sapiens. 2016-09-08. Retrieved 2017-05-28. "Statistics & Downloads for chromosome X". HUGO Gene Nomenclature Committee...

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S100 protein

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often been hyphenated, but current gene and protein nomenclature, such as HUGO Gene Nomenclature Committee nomenclature, does not use hyphens in symbols...

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Azoospermia factor

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spermatozoa in the ejaculate) males. AZF is the term used by the HUGO Gene Nomenclature Committee. Of the 15% of couples who are affected by infertility, 50%...

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Systematic name

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(administered by the International Astronomical Union) Genes (following HUGO Gene Nomenclature Committee procedures) Proteins Minerals (administered by the...

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BRCA2

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currently BRCA2, DNA repair associated) are maintained by the HUGO Gene Nomenclature Committee. One alternative symbol, FANCD1, recognizes its association...

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Microsoft Excel

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Excel. In August 2020 the HUGO Gene Nomenclature Committee (HGNC) published new guidelines in the journal Nature regarding gene naming in order to avoid...

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Chromosome 1

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human genes". Genome Biol. 11 (5): 206. doi:10.1186/gb-2010-11-5-206. PMC 2898077. PMID 20441615. "Statistics & Downloads for chromosome 1". HUGO Gene Nomenclature...

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Chromosome 8

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Human Cytogenetic Nomenclature (2013). Arbitrary unit. gpos: Region which is positively stained by G banding, generally AT-rich and gene poor; gneg: Region...

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Tumor necrosis factor

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as TNFβ, TNFα, as the previous gene symbol, is now simply called TNF, as shown in HGNC (HUGO Gene Nomenclature Committee) database. ENSG00000230108, ENSG00000223952...

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