Human gene database maintained by the Weizmann Institute of Science
GeneCards
Content
Data types captured
Human genes and model orthologues
Organisms
Homo sapiens
Contact
Research center
Crown Human Genome Center, WIS
Primary citation
PMID 9097728
Access
Data format
HTML
Website
www.genecards.org
GeneCards is a database of human genes that provides genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes.[1][2][3][4] It is being developed and maintained by the Crown Human Genome Center at the Weizmann Institute of Science, in collaboration with LifeMap Sciences.
The database aims at providing a comprehensive view of the current available biomedical information about the searched gene, including its aliases and identifiers, the encoded proteins, associated diseases and variations, its function, relevant publications and more.[1][5][6] The GeneCards database provides access to free Web resources about more than 350,000 known and predicted human genes, integrated from >150 data resources, such as HGNC, Ensembl, and NCBI. The core gene list is based on NCBI, Ensembl and approved gene symbols published by the HUGO Gene Nomenclature Committee (HGNC).[7][8] The information is carefully gathered and selected from these databases by its integration engine.
Over time, the GeneCards database has developed a suite of tools (VarElect, GeneALaCart, etc.) that have more specialised capabilities leveraging the database. Since 1998, the GeneCards database has been widely used by bioinformatics, genomics and medical communities for more than 24 years.[7][8]
^ abRebhan M, Chalifa-Caspi V, Prilusky J, Lancet D (April 1997). "GeneCards: integrating information about genes, proteins and diseases". Trends in Genetics. 13 (4): 163. doi:10.1016/S0168-9525(97)01103-7. PMID 9097728.
^Rebhan M, Chalifa-Caspi V, Prilusky J, Lancet D (1998). "GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support". Bioinformatics. 14 (8): 656–64. doi:10.1093/bioinformatics/14.8.656. PMID 9789091.
^Safran M, Solomon I, Shmueli O, Lapidot M, Shen-Orr S, Adato A, et al. (November 2002). "GeneCards 2002: towards a complete, object-oriented, human gene compendium". Bioinformatics. 18 (11): 1542–3. doi:10.1093/bioinformatics/18.11.1542. PMID 12424129.
^Harel A, Inger A, Stelzer G, Strichman-Almashanu L, Dalah I, Safran M, Lancet D (October 2009). "GIFtS: annotation landscape analysis with GeneCards". BMC Bioinformatics. 10 (1): 348. doi:10.1186/1471-2105-10-348. PMC 2774327. PMID 19852797.
^"GeneCards". GeneCards. Archived from the original on 2013-10-14. Retrieved 18 Oct 2013.
^"GeneCards". Retrieved 19 Oct 2013.
^ abCite error: The named reference pmid22155609 was invoked but never defined (see the help page).
^ abCite error: The named reference pmid20689021 was invoked but never defined (see the help page).
GeneCards is a database of human genes that provides genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted...
climaxed with him throwing cards into watermelon, first the squishy interior, then the "pachydermatic outer melon layer." Hochman, Gene; Dawson, Tom; Dawson...
(E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring gene family members that encode mitochondrial enzymes which...
pseudogene 1 is a protein that in humans is encoded by the TTC3P1 gene. GeneCards Symbol: TTC3P1 2 Tetratricopeptide Repeat Domain 3 Pseudogene 1 2 3...
169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. "GeneCards - Human Genes | Gene Database". Archived from the original on 2023-05-13. Retrieved...
20550–20554. doi:10.1016/S0021-9258(18)54960-7. PMID 1939106. "APOBEC1 Gene - GeneCards | ABEC1 Protein | ABEC1 Antibody". Archived from the original on 2011-07-26...
Olfactory receptor 6A2 is a protein that in humans is encoded by the OR6A2 gene. It is Class II (tetrapod-specific) olfactory receptor and a rhodopsin-like...
639–641. ISBN 9781464183393. "SAR1B Gene - Secretion Associated Ras Related GTPase 1B". GeneCards: The Human Gene Database. 4 October 2023. Retrieved...
from inside a cell. It is a protein that in humans is encoded by gene ABCC11. The gene is responsible for determination of human cerumen type (wet or dry...
neurobiochemical, and behavioral changes. Leptin is coded for by the LEP gene. Leptin receptors are expressed by a variety of brain and peripheral cell...
Atlas of Genetics and Cytogenetics in Oncology and Haematology TP53 Gene @ GeneCards p53 News provided by insciences organisation Goodsel DS (2002-07-01)...
protein that in humans is encoded by the EGFL7 gene. Intron 7 of EGFL7 hosts the miR-126 microRNA gene. Epidermal Growth Factor like domain 7 (Egfl7)...
Entrez Genome Project database NCBI Genome Primer GeneCards—an integrated database of human genes BBC News – Final genome 'chapter' published IMG (The...
kisspeptin-54 (KP-54), formerly known as metastin) are proteins encoded by the KISS1 gene in humans. Kisspeptins are ligands of the G-protein coupled receptor, GPR54...
(/ˌbrækəˈwʌn/) gene. Orthologs are common in other vertebrate species, whereas invertebrate genomes may encode a more distantly related gene. BRCA1 is a...
is encoded by the FOXP2 gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by binding to...
protein that in humans is encoded by the oculocutaneous albinism II (OCA2) gene. The P protein is believed to be an integral membrane protein involved in...
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