Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Fumonisin B1 is the most prevalent member of a family of toxins, known as fumonisins, produced by multiple species of Fusarium molds, such as Fusarium verticillioides,[1] which occur mainly in maize (corn), wheat and other cereals. Fumonisin B1 contamination of maize has been reported worldwide at mg/kg levels. Human exposure occurs at levels of micrograms to milligrams per day and is greatest in regions where maize products are the dietary staple.
Fumonisin B1 is hepatotoxic and nephrotoxic in all animal species tested. The earliest histological change to appear in either the liver or kidney of fumonisin-treated animals is increased apoptosis followed by regenerative cell proliferation. While the acute toxicity of fumonisin is low, it is the known cause of two diseases which occur in domestic animals with rapid onset: equine leukoencephalomalacia and porcine pulmonary oedema syndrome. Both of these diseases involve disturbed sphingolipid metabolism and cardiovascular dysfunction.
^Fumonisin B1 Archived February 11, 2009, at the Wayback Machine product specification by Fermentek
FumonisinB1 is the most prevalent member of a family of toxins, known as fumonisins, produced by multiple species of Fusarium molds, such as Fusarium...
sphingolipids. More specifically, it can refer to: FumonisinB1Fumonisin B2 Fumonisin B3 Fumonisin B4 As the fumonisins appear to be non-genotoxic the possibility...
found in Combretum sp. FumonisinB1, a toxins produced by several species of Fusarium molds B-1 cell, a lymphocyte type Arecatannin B1, a tannin found in...
analog of fumonisin B3, while it is lacking one hydroxy group compared to fumonisinB1. Fumonisin B2 is more cytotoxic than fumonisinB1. Fumonisin B2 inhibits...
lacking two hydroxy groups compared to fumonisinB1. Fumonisin B4 was first described in 1991. Several isomers of Fumonisin B4 have been detected. A larger group...
for pathogenicity on tomato. This host specific mycotoxin is called fumonisinB1. It was identified and confirmed by research conducted on fast atom bombardment...
Aflatoxin B1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus. It is a very potent carcinogen with a TD50 3.2 μg/kg/day in rats. This...
health risks due to contamination with the mycotoxins, aflatoxin B1 and fumonisinB1. Sugarcane juice, known locally as caldo de cana, is commonly sold...
E, Mduma ER, Patil CL, Wu F (March 2018). "Exposure to aflatoxin and fumonisin in children at risk for growth impairment in rural Tanzania". Environment...
Merrill AH, Riley RT (February 2009). "Ceramide synthase inhibition by fumonisinB1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive...
mycotoxins causing human and animal illness include aflatoxin, citrinin, fumonisins, ochratoxin A, patulin, trichothecenes, zearalenone, and ergot alkaloids...