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Fibril information


Hierarchical structure of hair in the cortex and cuticle, highlighting the scale which defines fibrils.

Fibrils (from the Latin fibra[1]) are structural biological materials found in nearly all living organisms. Not to be confused with fibers or filaments, fibrils tend to have diameters ranging from 10 to 100 nanometers (whereas fibers are micro to milli-scale structures and filaments have diameters approximately 10–50 nanometers in size). Fibrils are not usually found alone but rather are parts of greater hierarchical structures commonly found in biological systems. Due to the prevalence of fibrils in biological systems, their study is of great importance in the fields of microbiology, biomechanics, and materials science.

  1. ^ "Online Etymology Dictionary". www.etymonline.com. Retrieved 2017-03-31.

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Fibril

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Fibrils (from the Latin fibra) are structural biological materials found in nearly all living organisms. Not to be confused with fibers or filaments,...

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Amyloid

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amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by...

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Collagen

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consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such...

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Myofibril

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A myofibril (also known as a muscle fibril or sarcostyle) is a basic rod-like organelle of a muscle cell. Skeletal muscles are composed of long, tubular...

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Anchoring fibrils

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Anchoring fibrils (composed largely of type VII collagen) extend from the basal lamina of epithelial cells and attach to the lamina reticularis (also...

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Cell nucleus

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the protein components instead form a perinucleolar cap. Perichromatin fibrils are visible only under electron microscope. They are located next to the...

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Tendon

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which is a delicate loose connective tissue containing thin collagen fibrils and elastic fibers. A set of fascicles is bound by an epitenon, which is...

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Solar spicule

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In solar physics, a spicule, also known as a fibril or mottle, is a dynamic jet of plasma in the Sun's chromosphere about 300 km in diameter. They move...

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Cornea

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composed primarily of randomly organized yet tightly woven collagen fibrils. These fibrils interact with and attach onto each other. This layer is eight to...

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Amylin

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have shown that fibrils are the end product and not necessarily the most toxic form of amyloid proteins/peptides in general. A non-fibril forming peptide...

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Transthyretin

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(FAC). TTR tetramer dissociation is known to be rate-limiting for amyloid fibril formation. However, the monomer also must partially denature in order for...

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Stroma of cornea

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non-aqueous constituents of the stroma are collagen fibrils and proteoglycans. The collagen fibrils are made of a mixture of type I and type V collagens...

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Prion

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account fibril breakage. A mathematical solution for the exponential growth rate resulting from the combination of fibril growth and fibril breakage...

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Fibrillogenesis

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development of fine fibrils normally present in collagen fibers of connective tissue. It is derived from the New Latin fibrilla (meaning fibrils, or pertaining...

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Amyloidosis

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Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs and...

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Type V collagen

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that Type V collagen is responsible for the formation of other collagen fibrils in different tissues within the body. According to studies, Collagen V...

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Cotton

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Primary wall is mainly cellulose, it is made up of a network of fine fibrils (small strands of cellulose). The winding layer is the first layer of secondary...

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Achilles tendon

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retro-achilles bursitis. Within the tendon, increased blood flow, tendon fibril disorganisation, and partial thickness tears may be identified. Achilles...

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Protein aggregation predictors

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López de la; Serrano, Luis (2004-01-06). "Sequence determinants of amyloid fibril formation". Proceedings of the National Academy of Sciences. 101 (1): 87–92...

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Type I collagen

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by mainly hydrogen bonds and the fibrils conform to a typical diameter size between 25 - 400 nanometers in this fibril conformation.    Mutations in genes...

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Proteinopathy

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Sup35, and curli fibrils from the bacterium Escherichia coli. AII amyloid can be induced in mice by a variety of β-sheet rich amyloid fibrils, and cerebral...

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SCOBY

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structures extending from their cell membranes called fibrils. The nanocellulose composing these fibrils demonstrates great strength and stability while still...

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Coagulation

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hemostasis". Activated platelets contract their internal actin and myosin fibrils in their cytoskeleton, which leads to shrinkage of the clot volume. Plasminogen...

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Bacterial cellulose

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walls of most plants, is a tough, mesh-like bulkwork in which cellulose fibrils are the primary architectural elements. While bacterial cellulose has the...

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Tryptophan

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↓4-Hydroxy-2-nonenal levels ↓DNA damage –Antioxidant –Inhibits β-amyloid fibril formation Maintains mucosal reactivity: ↑IL-22 production Associated with...

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Protein

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specifically to other copies of the same molecule, they can oligomerize to form fibrils; this process occurs often in structural proteins that consist of globular...

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Thioflavin

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(ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39)"....

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Cellulose

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lengths.: 3384  Cellulose consists of fibrils with crystalline and amorphous regions. These cellulose fibrils may be individualized by mechanical treatment...

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Gut microbiota

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↓4-Hydroxy-2-nonenal levels ↓DNA damage –Antioxidant –Inhibits β-amyloid fibril formation Maintains mucosal reactivity: ↑IL-22 production Associated with...

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