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Etoperidone information


Etoperidone
Clinical data
Trade namesSeveral
Other namesST-1191; McN-A-2673-11
Routes of
administration
By mouth
ATC code
  • N06AB09 (WHO)
Identifiers
IUPAC name
  • 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-4,5-diethyl-1,2,4-triazol-3-one
CAS Number
  • 52942-31-1 checkY
PubChem CID
  • 40589
ChemSpider
  • 37083 checkY
UNII
  • KAI6MVO39Z
ChEMBL
  • ChEMBL1743259 ☒N
CompTox Dashboard (EPA)
  • DTXSID0023034 Edit this at Wikidata
Chemical and physical data
FormulaC19H28ClN5O
Molar mass377.92 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • Clc3cccc(N2CCN(CCCN1/N=C(\N(C1=O)CC)CC)CC2)c3
InChI
  • InChI=1S/C19H28ClN5O/c1-3-18-21-25(19(26)24(18)4-2)10-6-9-22-11-13-23(14-12-22)17-8-5-7-16(20)15-17/h5,7-8,15H,3-4,6,9-14H2,1-2H3 checkY
  • Key:IZBNNCFOBMGTQX-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed.[1][2][3] It is a phenylpiperazine related to trazodone and nefazodone in chemical structure and is a serotonin antagonist and reuptake inhibitor (SARI) similarly to them.[4]

  1. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. p. 421. ISBN 978-3-88763-075-1.
  2. ^ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia. Elsevier. pp. 1533–. ISBN 978-0-8155-1856-3.
  3. ^ Akritopoulou-Zanze I (16 August 2012). "Arylpiperazine-Based 5-HT1A Receptor Partial Agonists and 5-HT2A Antagonists for the Treatment of Autism, Depression, Anxiety, Psychosis, and Schizophrenia". In Lamberth C, Dinges J (eds.). Bioactive Heterocyclic Compound Classes: Pharmaceuticals. John Wiley & Sons. pp. 81–97. doi:10.1002/9783527664450.ch6. ISBN 978-3-527-66447-4.
  4. ^ Morrison-Valfre M (23 August 2016). Foundations of Mental Health Care - E-Book. Elsevier Health Sciences. pp. 245–. ISBN 978-0-323-37104-9.

and 27 Related for: Etoperidone information

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Etoperidone

Last Update:

Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was...

Word Count : 877

Phenylpiperazine

Last Update:

[91315-34-3] [34675-77-9] Clodoxopone [71923-34-7] Dropropizine [17692-31-8] Etoperidone FAUC-299 [313972-96-2] FAUC-312 [562104-72-7] LASSBio-579 [591774-47-9]...

Word Count : 198

Trazodone

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and a phenylpiperazine that is structurally related to nefazodone and etoperidone, each of which are derivatives of it. Trazodone was developed in Italy...

Word Count : 9966

Mepiprazole

Last Update:

Similarly to other phenylpiperazines like trazodone, nefazodone, and etoperidone, mepiprazole produces mCPP as an active metabolite. Acaprazine Enpiprazole...

Word Count : 537

Serotonin antagonist and reuptake inhibitor

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currently marketed SARIs belong to the phenylpiperazine class of compounds. Etoperidone (Axiomin, Etonin) Lorpiprazole (Normarex) Mepiprazole (Psigodal) Nefazodone...

Word Count : 615

Cocaine

Last Update:

Selective serotonin reuptake inhibitors and serotonin receptor modulators: Etoperidone Litoxetine Lubazodone LY-393558 Quipazine SB-649915 TGBA01AD Trazodone...

Word Count : 17673

Lorpiprazole

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reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone. Acaprazine Enpiprazole Mepiprazole Tolpiprazole Elks J (14 November...

Word Count : 128

List of antidepressants

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Serzone) – withdrawn/discontinued in most countries Trazodone (Desyrel) Etoperidone (Axiomin, Etonin) Reboxetine (Edronax) Teniloxazine (Lucelan, Metatone)...

Word Count : 1411

ATC code N06

Last Update:

Paroxetine N06AB06 Sertraline N06AB07 Alaproclate N06AB08 Fluvoxamine N06AB09 Etoperidone N06AB10 Escitalopram N06AF01 Isocarboxazid N06AF02 Nialamide N06AF03...

Word Count : 441

Rilmenidine

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acetergamine, ergotamine, dihydroergotamine, lisuride, nicergoline, terguride) Etoperidone Fenspiride Hydroxyzine Indoramin Ketanserin L-765,314 mCPP Mepiprazole...

Word Count : 758

Sedative

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Propiomazine Antidepressants Serotonin antagonists and reuptake inhibitors Etoperidone Nefazodone Trazodone Tricyclic antidepressants Amitriptyline Doxepin...

Word Count : 2419

Methaqualone

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Propiomazine Antidepressants Serotonin antagonists and reuptake inhibitors Etoperidone Nefazodone Trazodone Tricyclic antidepressants Amitriptyline Doxepin...

Word Count : 2382

Insomnia

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Propiomazine Antidepressants Serotonin antagonists and reuptake inhibitors Etoperidone Nefazodone Trazodone Tricyclic antidepressants Amitriptyline Doxepin...

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Buspirone

Last Update:

Setiptiline SARIsTooltip Serotonin antagonist and reuptake inhibitors Etoperidone Nefazodone Trazodone SMSTooltip Serotonin modulator and stimulators Vilazodone...

Word Count : 3769

Adrenaline

Last Update:

acetergamine, ergotamine, dihydroergotamine, lisuride, nicergoline, terguride) Etoperidone Fenspiride Hydroxyzine Indoramin Ketanserin L-765,314 mCPP Mepiprazole...

Word Count : 6615

MDMA

Last Update:

Agonists: 8-OH-DPAT Adatanserin Amphetamine Antidepressants (e.g., etoperidone, hydroxynefazodone, nefazodone, trazodone, triazoledione, vilazodone, vortioxetine)...

Word Count : 15730

Duloxetine

Last Update:

Setiptiline SARIsTooltip Serotonin antagonist and reuptake inhibitors Etoperidone Nefazodone Trazodone SMSTooltip Serotonin modulator and stimulators Vilazodone...

Word Count : 7230

Ketamine

Last Update:

Selective serotonin reuptake inhibitors and serotonin receptor modulators: Etoperidone Litoxetine Lubazodone LY-393558 Quipazine SB-649915 TGBA01AD Trazodone...

Word Count : 11403

Mirtazapine

Last Update:

Setiptiline SARIsTooltip Serotonin antagonist and reuptake inhibitors Etoperidone Nefazodone Trazodone SMSTooltip Serotonin modulator and stimulators Vilazodone...

Word Count : 7806

LSD

Last Update:

acetergamine, ergotamine, dihydroergotamine, lisuride, nicergoline, terguride) Etoperidone Fenspiride Hydroxyzine Indoramin Ketanserin L-765,314 mCPP Mepiprazole...

Word Count : 16528

Lemborexant

Last Update:

Propiomazine Antidepressants Serotonin antagonists and reuptake inhibitors Etoperidone Nefazodone Trazodone Tricyclic antidepressants Amitriptyline Doxepin...

Word Count : 1687

Monoamine oxidase inhibitor

Last Update:

Setiptiline SARIsTooltip Serotonin antagonist and reuptake inhibitors Etoperidone Nefazodone Trazodone SMSTooltip Serotonin modulator and stimulators Vilazodone...

Word Count : 3892

Phencyclidine

Last Update:

Selective serotonin reuptake inhibitors and serotonin receptor modulators: Etoperidone Litoxetine Lubazodone LY-393558 Quipazine SB-649915 TGBA01AD Trazodone...

Word Count : 5322

C19H28ClN5O

Last Update:

mass: 377.91 g/mol, exact mass: 377.1982 u) may refer to: CJ-033466 Etoperidone This set index page lists chemical structure articles associated with...

Word Count : 56

Carvedilol

Last Update:

acetergamine, ergotamine, dihydroergotamine, lisuride, nicergoline, terguride) Etoperidone Fenspiride Hydroxyzine Indoramin Ketanserin L-765,314 mCPP Mepiprazole...

Word Count : 2614

Pentobarbital

Last Update:

Propiomazine Antidepressants Serotonin antagonists and reuptake inhibitors Etoperidone Nefazodone Trazodone Tricyclic antidepressants Amitriptyline Doxepin...

Word Count : 1924

Dimenhydrinate

Last Update:

Propiomazine Antidepressants Serotonin antagonists and reuptake inhibitors Etoperidone Nefazodone Trazodone Tricyclic antidepressants Amitriptyline Doxepin...

Word Count : 1350

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