Enflurane (2-chloro-1,1,2-trifluoroethyl difluoromethyl ether) is a halogenated ether. Developed by Ross Terrell in 1963, it was first used clinically in 1966. It was increasingly used for inhalational anesthesia during the 1970s and 1980s[2] but is no longer in common use.[3]
Enflurane is a structural isomer of isoflurane. It vaporizes readily, but is a liquid at room temperature.
^Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^Niedermeyer E, Lopes da Silva FH (2005). Electroencephalography: Basic Principles, Clinical Applications, and Related Fields. Lippincott Williams & Wilkins. p. 1156. ISBN 978-0-7817-5126-1.
^Hemmings Jr HC, Egan TD (2013). Pharmacology and Physiology for Anesthesia. doi:10.1016/C2009-0-41712-4. ISBN 9781437716795.
Enflurane (2-chloro-1,1,2-trifluoroethyl difluoromethyl ether) is a halogenated ether. Developed by Ross Terrell in 1963, it was first used clinically...
give off irritable and toxic fumes when exposed to flame. Together with enflurane and halothane, Isoflurane began to replace the flammable ethers used in...
ethyl ether used for maintenance of general anesthesia. Like halothane, enflurane, and isoflurane, it is a racemic mixture of (R) and (S) optical isomers...
as enflurane and isoflurane. The incidence of hepatic reactions with these agents is lower. The exact degree of hepatotoxic potential of enflurane is...
Greenstein LR, Hitt BA, Mazze RI (1976). "Metabolism and renal effect of enflurane in man". Anesthesiology. 44 (1): 44–53. doi:10.1097/00000542-197601000-00009...
administered more than 5 minutes after the start of the inhalation of enflurane, isoflurane, or halothane, or when a steady state has been achieved, the...
volatile anesthetics, including the commercial products methoxyflurane, enflurane, isoflurane, sevoflurane and desflurane. Alkyl chlorides Some low molecular...
nitrous oxide. Older, less popular volatile anaesthetics include halothane, enflurane, and methoxyflurane. Researchers are also actively exploring the use of...