Endothelial progenitor cell (or EPC) is a term that has been applied to multiple different cell types that play roles in the regeneration of the endothelial lining of blood vessels. Outgrowth endothelial cells are an EPC subtype committed to endothelial cell formation.[1] Despite the history and controversy, the EPC in all its forms remains a promising target of regenerative medicine research.
^Medina RJ, O'Neill CL, Humphreys MW, Gardiner TA, Stitt AW (2010). "Outgrowth endothelial cells: characterization and their potential for reversing ischemic retinopathy". Investigative Ophthalmology & Visual Science. 51 (11): 5906–13. doi:10.1167/iovs.09-4951. PMID 20554606.
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Endothelialprogenitorcell (or EPC) is a term that has been applied to multiple different cell types that play roles in the regeneration of the endothelial...
A progenitorcell is a biological cell that can differentiate into a specific cell type. Stem cells and progenitorcells have this ability in common. However...
The endothelium (pl.: endothelia) is a single layer of squamous endothelialcells that line the interior surface of blood vessels and lymphatic vessels...
Endothelial stem cells (ESCs) are one of three types of stem cells found in bone marrow. They are multipotent, which describes the ability to give rise...
and inflammation. Endothelialprogenitorcells (EPCs) are cells derived from the bone marrow which differentiate into endothelialcells to help support...
metastases. Endothelialprogenitorcells have been shown to have a strong influence on metastasis and angiogenesis. Endothelialprogenitorcells are important...
measure more mature progenitor or transit-amplifying cells rather than stem cells[citation needed]. Since hematopoietic stem cells cannot be isolated as...
number and function of bone-marrow derived endothelialprogenitorcells. and reduced ability of those cells to form blood vessels. Formation of additional...
Jain RK (Apr 2004). "Role of eNOS in neovascularization: NO for endothelialprogenitorcells". Trends in Molecular Medicine. 10 (4): 143–5. doi:10.1016/j...
from progenitorcells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type...
adult human body is estimated to contain about 30 trillion (3×1013) human cells, with the number varying between 20 to 40 trillion depending on factors...
blood cell. Examples of progenitorcells are vascular stem cells that have the capacity to become both endothelial or smooth muscle cells. In cell biology...
the COMBO Dual Therapy Stent. The COMBO Stent features active endothelialprogenitorcell (EPC) capture technology, which promotes the accelerated natural...
Genous is an endothelialprogenitorcell (EPC) capture technology manufactured by OrbusNeich that promotes the accelerated natural healing of the vessel...
Platelet endothelialcell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the...
Liver sinusoidal endothelialcells (LSECs) form the lining of the smallest blood vessels in the liver, also called the hepatic sinusoids. LSECs are highly...
computers Early Prostate Cancer programme Electronic Product Code Endothelialprogenitorcell Energy Performance Certificate × Epicattleya, an orchid genus...
daughter stem cells, whereas asymmetric division produces one stem cell and one progenitorcell with limited self-renewal potential. Progenitors can go through...
M, et al. (March 2000). "Transplantation of ex vivo expanded endothelialprogenitorcells for therapeutic neovascularization". Proceedings of the National...
blood cells, such as red blood cells (RBCs), immune cells, and even platelets all originate from the same progenitorcell, the hematopoietic stem cell (HSC)...
by pathogenic factors in the body's circulation due to a series of endothelialcells known as the blood–brain barrier, or BBB. The BBB prevents most infections...
bone) osteoclasts (resorb bone) endothelialcells, which form the sinusoids. These derive from endothelial stem cells, which are also present in the bone...
factor (PDGF)-B and mesangial cells have receptors for PDGF. This induces mesangial cells to attach to endothelialcells causing developing blood vessels...
neurons, cancer cells, kidney and epithelial cells ). In vitro, VEGF-A has been shown to stimulate endothelialcell mitogenesis and cell migration. VEGF-A...
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