Therapy in which cellular material is injected into a patient
See also: Stem cell therapy and Immunotherapy
For the Goodie Mob song, see Cell Therapy (song).
Adoptive T-cell therapy. Cancer specific T-cells can be obtained by fragmentation and isolation of tumour infiltrating lymphocytes, or by genetically engineering cells from peripheral blood. The cells are activated and grown prior to transfusion into the recipient (tumour bearer).
Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect,[1] for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or grafting stem cells to regenerate diseased tissues.
Cell therapy originated in the nineteenth century when scientists experimented by injecting animal material in an attempt to prevent and treat illness.[2] Although such attempts produced no positive benefit, further research found in the mid twentieth century that human cells could be used to help prevent the human body rejecting transplanted organs, leading in time to successful bone marrow transplantation as has become common practice in treatment for patients that have compromised bone marrow after disease, infection, radiation or chemotherapy.[3] In recent decades, however, stem cell and cell transplantation has gained significant interest by researchers as a potential new therapeutic strategy for a wide range of diseases, in particular for degenerative and immunogenic pathologies.
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Celltherapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted...
the surface of tumor cells. Vaccine-induced immunity to COVID-19 relies mostly on an immunomodulatory T-cell response. Therapies such as granulocyte colony-stimulating...
antigen-binding and T cell activating functions into a single receptor. CAR T celltherapy uses T cells engineered with CARs to treat cancer. T cells are modified...
foreign DNA to cultured cells collected from patients suffering from the disease. The first attempt, an unsuccessful one, at gene therapy (as well as the first...
pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology...
(hydroxyurea). In 2023, new gene therapies were approved. A small percentage of people can be cured by a transplant of bone marrow cells. As of 2015[update], about...
embryonic stem cell cycle. Due to their plasticity and potentially unlimited capacity for self-renewal, embryonic stem celltherapies have been proposed...
receive some kind of therapy. In some cases, NK celltherapy is a choice. NK cells are known for their ability to eradicate tumor cells without any prior...
immunotherapies are T celltherapies. Other therapies include CAR-T therapy, CAR-NK therapy, macrophage-based immunotherapy and dendritic celltherapy. Although immunotherapy...
activity as a potential cancer therapy and HIV therapy. In early experiments on cell-mediated cytotoxicity against tumor target cells, both in cancer patients...
Somatic cell nuclear transfer is a cloning method that can be used to create a cloned embryo for the use of its embryonic stem cells in stem celltherapy. In...
with steroids, chemotherapy, targeted therapy, and stem cell transplant. Bisphosphonates and radiation therapy are sometimes used to reduce pain from...
leukemia. Treatment can also include radiation therapy if spread to the brain has occurred. Stem cell transplantation may be used if the disease recurs...
September 1971) was a Swiss surgeon. He is best known for developing fresh celltherapy, a form of alternative medicine. Due to unproven rumors that he had treated...
American Society of Gene & CellTherapy (ASGCT) is a professional non-profit medical and scientific organization based in Milwaukee, dedicated to understanding...
allergenics, somatic cells, gene therapies, tissues, recombinant therapeutic protein, and living medicines used in celltherapy. Biologics can be composed...
SS (2022-06-16). "CAR T celltherapy and the tumor microenvironment: Current challenges and opportunities". Molecular Therapy - Oncolytics. 25: 69–77...
control the growth of malignant cells. It is normally delivered by a linear particle accelerator. Radiation therapy may be curative in a number of types...
field of bio-inspired robotics. Stem celltherapy is an intervention strategy that introduces new adult stem cells into damaged tissue in order to treat...
inhibitors such as olaparib. Other therapies include hyperthermia, immunotherapy, photodynamic therapy, and stem-celltherapy. Most commonly cancer treatment...
regenerative medicine therapy is defined in section 506(g)(8) of the FD&C Act to include celltherapies, therapeutic tissue engineering, human cell and tissue products...
T cell receptor T celltherapy (TCR-T) is a type of adoptive T-celltherapy that targets some cancers. TCR-T therapies use heterodimers made of alpha and...
et al. (July 2018). "Paramount therapy for young and fit patients with mantle cell lymphoma: strategies for front-line therapy". J. Exp. Clin. Cancer Res...
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