Deoxyribonuclease X (EC 3.1.22.5, Escherichia coli endodeoxyribonuclease, Escherichia coli endodeoxyribonuclease X) is an enzyme.[1] This enzyme catalyses the following chemical reaction
Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes
This enzyme has preference for supercoiled DNA.
^DasGupta U, Ghosh S (March 1983). "Identification of a new deoxyendonuclease from Escherichia coli that preferentially cleaves supercoiled plasmid DNA". FEBS Letters. 153 (1): 60–4. doi:10.1016/0014-5793(83)80119-7. PMID 6219007.
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It is particularly effective for Gram-positive bacteria. b. DNase (Deoxyribonuclease): DNase degrades DNA present in the lysate, reducing its viscosity...
tracheobronchoplasty, and tracheostomy. The role of the nebulised recombinant human deoxyribonuclease (rhDNase) remains inconclusive. Tracheal collapse for the condition...
like hyaluronidase, lipase, collagenase, elastase, ribonuclease, deoxyribonuclease also play an important role in preventing the spread of infection...
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treated in ambulatory settings is not known. Inhaled recombinant human deoxyribonuclease (rhDNase), an enzyme that digests the DNA that contributes to mucus...
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spreading factor) breaks down hyaluronic acid and helps in spreading it. Deoxyribonuclease, which breaks down the DNA, protects S. aureus from neutrophil extracellular...
Enriquez A, Chu IW, Mellis C, Lin WY (November 2012). "Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months". The Cochrane...
Deoxyribonuclease-1-like 2 is an enzyme that in humans is encoded by the DNASE1L2 gene. GRCh38: Ensembl release 89: ENSG00000167968 – Ensembl, May 2017...
56-bp variable number of tandem repeat polymorphisms within the human deoxyribonuclease I gene". Legal Medicine. 17 (4): 283–6. doi:10.1016/j.legalmed.2015...
S2CID 205499369. Lacks S, Greenberg B, Neuberger M (June 1974). "Role of a deoxyribonuclease in the genetic transformation of Diplococcus pneumoniae". Proceedings...
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