"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior to the syncytiotrophoblast and external to the wall of the blastocyst in a developing embryo.
The cytotrophoblast is considered to be the trophoblastic stem cell because the layer surrounding the blastocyst remains while daughter cells differentiate and proliferate to function in multiple roles. There are two lineages that cytotrophoblastic cells may differentiate through: fusion and invasive. The fusion lineage yields syncytiotrophoblast and the invasive lineage yields interstitial cytotrophoblast cells.[1]
Cytotrophoblastic cells play an important role in the implantation of an embryo in the uterus.
^Handwerger, S (8 July 2010). "New insights into the regulation of human cytotrophoblast cell differentiation". Molecular and Cellular Endocrinology. 323 (1): 94–104. doi:10.1016/j.mce.2009.12.015. PMC 2874088. PMID 20036312.
"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior...
surrounded by two layers of trophoblasts, the cytotrophoblast and the syncytiotrophoblast. The cytotrophoblast is a layer of mono-nucleated cells that resides...
differentiates into an inner layer, the cytotrophoblast, and an outer layer, the syncytiotrophoblast. The cytotrophoblast contains cuboidal epithelial cells...
The cytotrophoblastic shell is the external layer of cytotrophoblasts from the fetus that is found on the maternal surface of the placenta. The cytotrophoblastic...
Heuser's membrane cells (hypoblast cells) that migrated along the inner cytotrophoblast lining of the blastocoel, secrete an extracellular matrix along the...
proliferative capacity and instead is maintained by fusion of underlying cytotrophoblast cells. This fusion is assisted by syncytin, a protein that was integrated...
is made up of an internal layer of cubical or prismatic cells, the cytotrophoblast or layer of Langhans, and an external multinucleated layer, the syncytiotrophoblast...
cells also secrete factors to make the blastocoel. After implantation, cytotrophoblast is the inner layer of the trophoblast, composed of stem cells which...
They often surround the cytotrophoblasts, reminiscent of their normal anatomical relationship in chorionic villi. Cytotrophoblasts are polyhedral, mononuclear...
is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast. It is sub-categorized by location: Villous intermediate trophoblast:...
tissues are PEG10 and the cancer testis antigen PAGE4 and expressed in cytotrophoblasts, CSH1 and KISS1 expressed in syncytiotrophoblasts, and PAPPA2 and PRG2...
endocrinology of human placenta (II): hormone secreting activity of cytotrophoblast cells. Sci China B., 34, 1092–1097.) Gerami-Naini, B. et al (2004)...
(exocoelomic cavity) lining. Some hypoblast cells migrate along the inner cytotrophoblast lining of the blastocoel, secreting an extracellular matrix along the...
Hamilton WJ (July 1966). "Electron microscopic observations on the cytotrophoblast contribution to the syncytium in the human placenta". Journal of Anatomy...
(endoderm, mesoderm, or ectoderm), or into cells of the placenta (cytotrophoblast or syncytiotrophoblast). After reaching a 16-cell stage, the totipotent...
intervillous space. They exhibit a bi-layered epithelium consisting of cytotrophoblasts with overlaying syncytium (syncytiotrophoblast). Anchoring (stem) villi...
part of the blastocyst) divides to form two separate layers: an inner cytotrophoblast layer, and an outer syncytiotrophoblast layer. Using enzymes, the syncytiotrophoblast...
cells), termed the syncytiotrophoblast, while the inner layer, the cytotrophoblast, consists of well-defined cells. As already stated, the cells of the...
developing placental-uterine interface. EVTs derive from progenitor cytotrophoblasts (CYTs), as does the other main trophoblast subtype, syncytiotrophoblast...
A. M.; Monaghan, P. (August 1980). "Preparation of highly purified cytotrophoblast from human placenta with subsequent modulation to form syncytiotrophoblast...
cells are mainly found in the blastocystic cavity. syncytiotrophoblast cytotrophoblast amniotic ectoderm implantation bilaminar embryonic disc primary yolk...
Global Information
