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Amitosis information


Amitosis, also known as karyostenotic, direct cell division, or binary fission, represents a mode of asexual cell division predominantly observed in prokaryotes. This process is distinct from other cell division mechanisms such as mitosis and meiosis, primarily because it bypasses the complexities associated with the mitotic apparatus, such as spindle formation. Additionally, amitosis does not involve the condensation of chromatin into distinct chromosomes before the division of the cell occurs, simplifying the process of cellular replication.

Several instances of cell division formerly thought to be "non-mitotic", such as the division of some unicellular eukaryotes, may actually occur by the process of "closed mitosis", which is different from open or semi-closed mitotic processes, all of which involve mitotic chromosomes and are classified by nuclear envelope. Amitosis can also effect on the distribution of human lactic acid dehydrogenase isoenzyme which is present in almost all body tissue. Example of amitosis is spermatogenesis. When in the process of amitosis the cell membrane will not divide.

There are two or more nuclei which are called dinucleated and multinucleated cells respectively. Sometimes it is also formed by fusion of the cell. Amitosis differs fundamentally from mitosis without cytokinesis, yet still shares some similarities between amitosis and cell fusion. Amitosis can result in near haploid nuclei, which is not possible through mitosis or cell fusion.[1]

The mitotic index declines from 2.2% at day ten to 0.3% at day thirty during postnatal life. Delayed fixation yields degenerated prophase and telophase nuclei only. [2]

  1. ^ Kuhn, E. M.; Therman, E.; Susman, B. (1991). "Amitosis and endocycles in early cultured mouse trophoblast". Placenta. 12 (3): 251–261. doi:10.1016/0143-4004(91)90006-2. PMID 1754574.
  2. ^ Pfitzer, P. (1980). "Amitosis: A Historical Misinterpretation?". Pathology, Research and Practice. 167 (2–4): 292–300. doi:10.1016/S0344-0338(80)80059-8. PMID 7433237.

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