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Intermediate trophoblast information


Micrograph showing intermediate trophoblasts. H&E stain.
Implantation site intermediate trophoblast. Low molecular weight cytokeratin stain.

Intermediate trophoblast is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast.[1]

It is sub-categorized by location:[1]

  • Villous intermediate trophoblast:
    • at anchoring villi of trophoblastic column
  • Implantation site intermediate trophoblast:
    • at implantation site (or basal plate), differentiated from villous intermediate trophoblast
  • Chorionic-type intermediate trophoblast
    • at chorionic laeve of fetal membrane, differentiated from villous intermediate trophoblast
  1. ^ a b Shih IM, Kurman RJ (January 2001). "The pathology of intermediate trophoblastic tumors and tumor-like lesions". Int. J. Gynecol. Pathol. 20 (1): 31–47. doi:10.1097/00004347-200101000-00004. PMID 11192071.

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Intermediate trophoblast

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villous intermediate trophoblast Chorionic-type intermediate trophoblast at chorionic laeve of fetal membrane, differentiated from villous intermediate trophoblast...

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Trophoblast

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The trophoblast (from Greek trephein: to feed; and blastos: germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days...

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Extravillous trophoblast

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(CYTs), as does the other main trophoblast subtype, syncytiotrophoblast (SYN). They are sometimes called intermediate trophoblast. EVTs that derive from CYT...

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Placental site trophoblastic tumor

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gestational trophoblastic disease, which is thought to arise from intermediate trophoblast. The tumor may secrete human placental lactogen, and result in...

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Syncytiotrophoblast

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of chorionic villi, with two knots pointed out. Cytotrophoblast Intermediate trophoblast Syncytium Zeldovich, Varvara B.; Bakardjiev, Anna I. (2012-08-09)...

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Gestational trophoblastic disease

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Exaggerated placental site Placental site nodule Both are composed of intermediate trophoblast, but their morphological features and clinical presentation can...

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Cytokeratin

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cytoskeleton of epithelial tissue. They are an important component of intermediate filaments, which help cells resist mechanical stress. Expression of these...

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Human embryonic development

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of cells called the trophoblast, and an inner cell mass. With further compaction the individual outer blastomeres, the trophoblasts, become indistinguishable...

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Trophoblastic neoplasm

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included in gestational trophoblastic disease (GTD) in which abnormal trophoblast cells grow in the uterus. GTN can be classified into benign and malignant...

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Epithelioid trophoblastic tumour

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trophoblastic tumor of neoplastic chorionic type associated with the intermediate trophoblast. Vaginal bleeding: The most common presenting symptom is vaginal...

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Decidua

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together with the placenta. The part of the decidua that interacts with the trophoblast is the decidua basalis (also called decidua placentalis), while the decidua...

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Gestational choriocarcinoma

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There are three different types of trophoblasts: cytotrophoblasts, syncytiotrophoblasts, and intermediate trophoblasts. Each of them possesses distinct...

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Villitis of unknown etiology

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epithelial syncytiotrophoblast as the villi mature into invasive intermediate trophoblasts through the developmental course of the placenta. A trophic factor...

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Animal embryonic development

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but soon they become arranged into an outer or peripheral layer, the trophoblast, which does not contribute to the formation of the embryo proper, and...

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Cytotrophoblast

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"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior...

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Placenta

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specific. The corresponding specific proteins are mainly expressed in trophoblasts and have functions related to pregnancy. Examples of proteins with elevated...

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Germ layer

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then changes to a blastocyst, consisting of an outer layer called a trophoblast, and an inner cell mass called the embryoblast. Filled with uterine fluid...

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Carnegie stages

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eight-cell stage, compaction usually begins. blastocyst and blastocoele trophoblast and embryoblast Carnegie stage 3 begins when a cavity first appears in...

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Chorionic villi

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rather than an ectopic pregnancy. Micrograph showing chorionic villi. Intermediate magnification. H&E stain. Micrograph showing chorionic villi. Very high...

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Bilaminar embryonic disc

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primitive yolk sac and the amniotic sac. The epiblast is adjacent to the trophoblast and made of columnar epithelial cells; the hypoblast is closest to the...

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Paracrine signaling

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"Nodal and ALK7 Inhibit Proliferation and Induce Apoptosis in Human Trophoblast Cells". Journal of Biological Chemistry. 279 (30): 31277–86. doi:10.1074/jbc...

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Amitosis

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result in representative transmission of chromatin. In rat polyploid trophoblasts, the nuclear envelope of the giant nucleus is involved in this subdivision...

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Seminoma

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elevated in some cases, but this correlates more to the presence of trophoblast cells within the tumour than to the stage of the tumour. A classical...

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Embryonic differentiation waves

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outside of the early ball of cells and they become determined to be trophoblast. Cells on the inside of the ball contract instead due to the mechanical...

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Cytokine

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reproduction, i.e. embryo implantation, endometrial development, and trophoblast growth and differentiation by modulating the immune and endocrine systems...

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List of distinct cell types in the adult human body

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Intestine None None unknown None NOVA2, SOX17 endovascular extravillous trophoblast unknown unknown placenta None None unknown None HLA-G, KRT7, MCAM, CDH5...

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Embryomics

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sphere of cells called the trophoblast and an inner cell mass called the embryoblast. The spherical outer cell layer (trophoblast), after implantation in...

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