Clobazam, sold under the brand names Frisium, Onfi and others, is a benzodiazepine class medication that was patented in 1968.[3] Clobazam was first synthesized in 1966 and first published in 1969. Clobazam was originally marketed as an anxioselective anxiolytic since 1970,[4][5] and an anticonvulsant since 1984.[6] The primary drug-development goal was to provide greater anxiolytic, anti-obsessive efficacy with fewer benzodiazepine-related side effects.[4]
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^Anvisa (31 March 2023). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 4 April 2023). Archived from the original on 3 August 2023. Retrieved 16 August 2023.
^"Clobazam (T3D4564)". Toxin and Toxin Target Database (T3DB.
^ abHumayun MJ, Samanta D, Carson RP (2020). "Clobazam". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 31082087.
^Freche C (April 1975). "[Study of an anxiolytic, clobazam, in otorhinolaryngology in psychosomatic pharyngeal manifestations]". Semaine des Hopitaux. Therapeutique. 51 (4): 261–3. PMID 5777.
^"Clobazam in treatment of refractory epilepsy: the Canadian experience. A retrospective study. Canadian Clobazam Cooperative Group". Epilepsia. 32 (3): 407–16. 1991. doi:10.1111/j.1528-1157.1991.tb04670.x. PMID 2044502. S2CID 24420211.
Clobazam, sold under the brand names Frisium, Onfi and others, is a benzodiazepine class medication that was patented in 1968. Clobazam was first synthesized...
the European Union, stiripentol is indicated for use in conjunction with clobazam and valproate as adjunctive therapy of refractory generalized tonic-clonic...
contraception is less clear than that of the strong enzyme-inducing ASMs. Clobazam, eslicarbazepine, felbamate, lamotrigine, rufinamide and topiramate are...
difficult to manage but may be reduced by anticonvulsant medications such as clobazam, stiripentol, topiramate and valproate. Because the course of the disorder...
lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam. Lofendazam as a human pharmaceutical has sedative and anxiolytic effects...
therapy. Clobazam is widely used by specialist epilepsy clinics worldwide and clonazepam is popular in the Netherlands, Belgium and France. Clobazam was approved...
– an antidepressant of the SNRI class Frisium, Onfi, Tapclob, Urbanol (clobazam) – a benzodiazepine that has been marketed as an anxiolytic since 1975...
derivative, related to clobazam. It has sedative and anxiolytic effects, with a long half-life and duration of action. Benzodiazepine Clobazam CP-1414S Triflunordazepam...
benzodiazepines marketed in Sweden (alprazolam, clonazepam, lorazepam, clobazam, and bromazepam) were negligible. When calculated in relation to utilization...
dependency. Of many drugs in this class, only a few are used to treat epilepsy: Clobazam (1979). Notably, used on a short-term basis around menstruation in women...
associated with Lennox–Gastaut syndrome or Dravet syndrome, in conjunction with clobazam, for people two years of age and older. In 2020, the label for Epidiolex...
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