Stiripentol information

Stiripentol
Clinical data
Pronunciation	stir"i pen' tol
Trade names	Diacomit
AHFS/Drugs.com	Monograph
MedlinePlus	a618069
License data	EU EMA: by INN; US DailyMed: Stiripentol;
Pregnancy; category	AU: B3; ;
Routes of; administration	By mouth
ATC code	N03AX17 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); CA: ℞-only; UK: POM (Prescription only); US: ℞-only; EU: ; In general: ℞ (Prescription only);
Identifiers
	IUPAC name (RS)-(E)-4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol;
CAS Number	137767-55-6 ;
PubChem CID	5311454;
IUPHAR/BPS	5469;
DrugBank	DB09118 ;
ChemSpider	4470940 ;
UNII	R02XOT8V8I;
KEGG	D05928 ;
ChEMBL	ChEMBL1983350;
CompTox Dashboard (EPA)	DTXSID6049068 ;
ECHA InfoCard	100.051.329
Chemical and physical data
Formula	C14H18O3
Molar mass	234.295 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O1c2ccc(cc2OC1)/C=C/C(O)C(C)(C)C;
	InChI InChI=1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+ ; Key:IBLNKMRFIPWSOY-FNORWQNLSA-N ;
	(what is this?) (verify)

Stiripentol, sold under the brand name Diacomit, is an anticonvulsant medication used for the treatment of Dravet syndrome - a serious genetic brain disorder.^[5]^[6]

The most common side effects include loss of appetite, weight loss, insomnia (difficulty sleeping), drowsiness, ataxia (inability to co‑ordinate muscle movements), hypotonia (low muscle strength) and dystonia (muscle disorders).^[5]

^ ^a ^b "Diacomit". Therapeutic Goods Administration (TGA). 13 December 2019. Retrieved 17 September 2021.
^ ^a ^b "AusPAR: Stiripentol". Therapeutic Goods Administration (TGA). 19 December 2019. Retrieved 17 September 2021.
^ "Diacomit 250mg hard capsules - Summary of Product Characteristics (SmPC)". (emc). 31 May 2019. Retrieved 8 November 2020.
^ Cite error: The named reference Diacomit FDA label was invoked but never defined (see the help page).
^ ^a ^b ^c Cite error: The named reference Diacomit EPAR was invoked but never defined (see the help page).
^ "Stiripentol Monograph for Professionals". Drugs.com. 31 August 2020. Retrieved 8 November 2020.

[Diacomit_APM_summary-1] "Diacomit". Therapeutic Goods Administration (TGA). 13 December 2019. Retrieved 17 September 2021.

[AusPAR:_Stiripentol-2] "AusPAR: Stiripentol". Therapeutic Goods Administration (TGA). 19 December 2019. Retrieved 17 September 2021.

[3] "Diacomit 250mg hard capsules - Summary of Product Characteristics (SmPC)". (emc). 31 May 2019. Retrieved 8 November 2020.

[Diacomit_FDA_label-4] Cite error: The named reference Diacomit FDA label was invoked but never defined (see the help page).

[Diacomit_EPAR-5] Cite error: The named reference Diacomit EPAR was invoked but never defined (see the help page).

[6] "Stiripentol Monograph for Professionals". Drugs.com. 31 August 2020. Retrieved 8 November 2020.

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