attachment of mitotic spindle microtubules to kinetochore
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
1062
229841
Ensembl
ENSG00000138778
ENSMUSG00000045328
UniProt
Q02224
Q6RT24
RefSeq (mRNA)
NM_001286734 NM_001813
NM_173762
RefSeq (protein)
NP_001273663 NP_001804
NP_776123
Location (UCSC)
Chr 4: 103.11 – 103.2 Mb
Chr 3: 134.92 – 134.98 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Centromere-associated protein E is a protein that in humans is encoded by the CENPE gene.[5][6]
Centromere-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centromere-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.[6]
CENPE is also called Kinesin-7.
^ abcGRCh38: Ensembl release 89: ENSG00000138778 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000045328 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Testa JR, Zhou JY, Bell DW, Yen TJ (Mar 1995). "Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24→q25 and 1q32→q41, respectively, by fluorescence in situ hybridization". Genomics. 23 (3): 691–3. doi:10.1006/geno.1994.1558. PMID 7851898.
^ ab"Entrez Gene: CENPE centromere protein E, 312kDa".
and 28 Related for: Centromere protein E information
Centromere-associated proteinE is a protein that in humans is encoded by the CENPE gene. Centromere-associated proteinE is a kinesin-like motor protein...
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Global Information
