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Carbohydrate metabolism information


Carbohydrate metabolism is the whole of the biochemical processes responsible for the metabolic formation, breakdown, and interconversion of carbohydrates in living organisms.

Carbohydrates are central to many essential metabolic pathways.[1] Plants synthesize carbohydrates from carbon dioxide and water through photosynthesis, allowing them to store energy absorbed from sunlight internally.[2] When animals and fungi consume plants, they use cellular respiration to break down these stored carbohydrates to make energy available to cells.[2] Both animals and plants temporarily store the released energy in the form of high-energy molecules, such as adenosine triphosphate (ATP), for use in various cellular processes.[3]

Humans can consume a variety of carbohydrates, digestion breaks down complex carbohydrates into simple monomers (monosaccharides): glucose, fructose, mannose and galactose. After resorption in the gut, the monosaccharides are transported, through the portal vein, to the liver, where all non-glucose monosacharids (fructose, galactose) are transformed into glucose as well.[4] Glucose (blood sugar) is distributed to cells in the tissues, where it is broken down via cellular respiration, or stored as glycogen.[3][4] In cellular (aerobic) respiration, glucose and oxygen are metabolized to release energy, with carbon dioxide and water as endproducts.[2][4]

  1. ^ Maughan, Ron (2009). "Carbohydrate metabolism". Surgery (Oxford). 27 (1): 6–10. doi:10.1016/j.mpsur.2008.12.002.
  2. ^ a b c Nelson, David Lee (2013). Lehninger principles of biochemistry. Cox, Michael M., Lehninger, Albert L. (6th ed.). New York: W.H. Freeman and Company. ISBN 978-1429234146. OCLC 824794893.
  3. ^ a b Sanders, L. M. (2016). "Carbohydrate: Digestion, Absorption and Metabolism". Encyclopedia of Food and Health. pp. 643–650. doi:10.1016/b978-0-12-384947-2.00114-8. ISBN 9780123849533.
  4. ^ a b c Hall, John E. (2015). Guyton and Hall Textbook of Medical Physiology E-Book (13 ed.). Elsevier Health Sciences. ISBN 978-0323389303.

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Carbohydrate metabolism

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Inborn errors of carbohydrate metabolism

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Inborn errors of carbohydrate metabolism are inborn error of metabolism that affect the catabolism and anabolism of carbohydrates. An example is lactose...

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Carbohydrate

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A carbohydrate (/ˌkɑːrboʊˈhaɪdreɪt/) is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom...

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Liver

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by the lower right rib cage. Its other metabolic roles include carbohydrate metabolism, the production of hormones, conversion and storage of nutrients...

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Hepatocyte

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are involved in: Protein synthesis Protein storage Transformation of carbohydrates Synthesis of cholesterol, bile salts and phospholipids Detoxification...

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Metabolism

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carbohydrates, lipids, and nucleic acids). Usually, catabolism releases energy, and anabolism consumes energy. The chemical reactions of metabolism are...

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Cellular respiration

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Aerobic respiration requires oxygen (O2) in order to create ATP. Although carbohydrates, fats and proteins are consumed as reactants, aerobic respiration is...

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Urea cycle

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Valerie (2014-01-01), Makowski, Gregory S. (ed.), "Chapter Three - Ammonia Metabolism and Hyperammonemic Disorders", Advances in Clinical Chemistry, 67, Elsevier:...

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Hitting the wall

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hyperuricemia. In muscle glycogenoses (muscle GSDs), an inborn error of carbohydrate metabolism impairs either the formation or utilization of muscle glycogen...

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Psicose

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(November 2020). "Effect of fructose and its epimers on postprandial carbohydrate metabolism: A systematic review and meta-analysis". Clinical Nutrition. 39...

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Lipid metabolism

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Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown and storage of fats for energy and the synthesis of structural...

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Glucokinase

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important role in the regulation of carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to...

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Inborn errors of metabolism

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Errors of Metabolism, was published in 1923. Traditionally the inherited metabolic diseases were classified as disorders of carbohydrate metabolism, amino...

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Ketosis

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"Implementing a low-carbohydrate, ketogenic diet to manage type 2 diabetes mellitus". Expert Review of Endocrinology & Metabolism. 13 (5): 263–272. doi:10...

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Hereditary fructose intolerance

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Hereditary fructose intolerance (HFI) is an inborn error of fructose metabolism caused by a deficiency of the enzyme aldolase B. Individuals affected with...

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Gluconeogenesis

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pathway that results in the biosynthesis of glucose from certain non-carbohydrate carbon substrates. It is a ubiquitous process, present in plants, animals...

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Fructose

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(2006). Carbohydrate metabolism: Synthesis and oxidation. Missouri: Saunders, Elsevier. pp. 258–277. ISBN 978-1-4160-0209-3. Sul, HS (2006). Metabolism of...

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Glycogen

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treatment for this type of hypoglycemia. Various inborn errors of carbohydrate metabolism are caused by deficiencies of enzymes or transport proteins necessary...

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Steroid

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hydrogen atom. 'Deoxy' is extensively used as a subtractive prefix in carbohydrate nomenclature (see P‐102.5.3). "IUPAC-IUB Joint Commission on Biochemical...

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Glucose tolerance test

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sometimes reactive hypoglycemia and acromegaly, or rarer disorders of carbohydrate metabolism. In the most commonly performed version of the test, an oral glucose...

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Gerty Cori

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Historic Chemical Landmark in recognition of their work in clarifying carbohydrate metabolism. In 1957, Gerty Cori died after a ten-year struggle with myelosclerosis...

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Fructolysis

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two important enzymes in fructose metabolism results in the development of two inborn errors in carbohydrate metabolism – essential fructosuria and hereditary...

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Xanthan gum

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pentasaccharide repeat unit. This links the synthesis of xanthan to carbohydrate metabolism. The repeat units are built up at undecaprenylphosphate lipid carriers...

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Methylprednisolone

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derived after the discovery of their involvement in regulating carbohydrate metabolism. The cellular functions of glucocorticoids, such as methylprednisolone...

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Anaerobic respiration

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Junyoung O.; Mahendra, Shaily (2021). "Vinyl chloride and 1,4-dioxane metabolism by Pseudonocardia dioxanivorans CB1190". Journal of Hazardous Materials...

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Housekeeping gene

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sensor protein kinase that plays a key role in regulating cellular energy metabolism PRKAB1 NM_006253 Non-catalytic subunit of AMP-activated protein kinase...

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Corticosteroid

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stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. Some...

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Lactic acid bacteria

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Actinomycetota) also produce lactic acid as the major product of carbohydrate metabolism. The lactic acid bacteria (LAB) are either rod-shaped (bacilli)...

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Protein metabolism

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Protein metabolism denotes the various biochemical processes responsible for the synthesis of proteins and amino acids (anabolism), and the breakdown of...

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