Antipsychotic abuse refers to the non-medical or inappropriate use of antipsychotic medications for purposes other than their intended therapeutic use. Antipsychotics, also known as neuroleptics, are a class of medications primarily used in treating psychiatric disorders such as schizophrenia, bipolar disorder, and certain types of depression. The misuse and abuse (MUA) of pharmaceuticals are typically linked to medications that elicit euphoria or other desirable effects, such as relaxation or increased alertness. Consequently, antipsychotics are not commonly categorized as significant substances prone to abuse. However, antipsychotics abuse may be attributed to its calming and sedative effects, and they have been exploited to either enhance the effects of illicit substances like cocaine and marijuana or counteract their adverse consequences.[1] Due to the potential of physical, social, and psychological consequences in patients using antipsychotics, the prevention and protection of these patient populations from the MUA of drugs has been implemented via various legislations worldwide which differ depending on the local jurisdiction.
^Kim, Sean; Lee, Gayoung; Kim, Eric; Jung, Hyejin; Chang, Jongwha (2017). "Quetiapine Misuse and Abuse: Is it an Atypical Paradigm of Drug Seeking Behavior?". Journal of Research in Pharmacy Practice. 6 (1): 12–15. doi:10.4103/2279-042X.200987. ISSN 2319-9644. PMC 5348850. PMID 28331860.
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third-generation antipsychotic, as opposed to first-generation (typical) antipsychotics like haloperidol and second-generation (atypical) antipsychotics like clozapine...
positive symptoms are present. Both first-generation antipsychotics and second-generation antipsychotics may be useful. Since these delusions are often accompanied...
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was an American patient who sued a hospital for her right to refuse antipsychotic medication. The court decision significantly changed the approach to...
levels of comorbid antisocial and paranoid personality disorders, substance abuse, externalizing, unemployment and greater likelihood of violence. Of note...
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escalating doses of antipsychotics. Dopamine supersensitivity may be caused by the dopamine receptor D2 antagonizing effect of antipsychotics, causing a compensatory...
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prescription drug abuse became apparent. In one of the darkest moments of The Two Coreys, Haim told Feldman that he had been sexually abused at the age of...
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of choice to control agitation and seizures (when present). Typical antipsychotics such as phenothiazines and haloperidol have been used to control psychotic...
antidepressants or antipsychotics), hormonal therapy, and uterine tissue removal is adequate to treat the condition. Antipsychotics have been shown to...
μ-opioid receptor antagonists such as naltrexone and nalmefene, and antipsychotics like haloperidol and chlorpromazine (via blockade of dopamine receptors)...
the DSM-5, DSM-IV abuse and dependence were combined into cannabis use disorder. The legal problems criterion (from cannabis abuse) has been removed,...
abrupt withdrawal from benzodiazepines, even from therapeutic doses. Antipsychotics increase the severity of benzodiazepine withdrawal effects with an increase...
appear to be effective as treatment. Limited evidence suggests that antipsychotics are also ineffective for treatment of cocaine dependence. Few studies...
well as atypical antipsychotics such as aripiprazole—are the mainstay of long-term pharmacologic relapse prevention. Antipsychotics are additionally given...
insomnia is due to an underlying mental health condition treatable by antipsychotics as the risks frequently outweigh the benefits. Some of the more serious...
Azapirones are a class of drugs used as anxiolytics, antidepressants, and antipsychotics. They are commonly used as add-ons to other antidepressants, such as...
administration can be effective for reducing motor side-effects of antipsychotics, with both bradykinesia (stiff muscles) and dyskinesia (involuntary...
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