positive regulation of DNA-binding transcription factor activity
response to glucocorticoid
positive regulation of angiogenesis
positive regulation of endothelial cell migration
defense response to bacterium
animal organ regeneration
phagocytosis
response to growth factor
hippocampus development
homophilic cell adhesion via plasma membrane adhesion molecules
regulation of NMDA receptor activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
306
11745
Ensembl
ENSG00000138772
ENSMUSG00000029484
UniProt
P12429
O35639
RefSeq (mRNA)
NM_005139
NM_013470
RefSeq (protein)
NP_005130
NP_038498
Location (UCSC)
Chr 4: 78.55 – 78.61 Mb
Chr 5: 96.94 – 96.99 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Annexin A3 is a protein that in humans is encoded by the ANXA3 gene.[5][6]
It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART.[7]
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000138772 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000029484 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Tait JF, Frankenberry DA, Miao CH, Killary AM, Adler DA, Disteche CM (Aug 1991). "Chromosomal localization of the human annexin III (ANX3) gene". Genomics. 10 (2): 441–8. doi:10.1016/0888-7543(91)90330-H. PMID 1830024.
^ ab"Entrez Gene: ANXA3 annexin A3".
^Zhang Y, Zhang YL, Feng C, et al. (September 2008). "Comparative proteomic analysis of human placenta derived from assisted reproductive technology". Proteomics. 8 (20): 4344–56. doi:10.1002/pmic.200800294. PMID 18792929. S2CID 206362532.
AnnexinA3 is a protein that in humans is encoded by the ANXA3 gene. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to...
regulatory sequence, a sequence for the insulin gene Adenosine A3 receptor, a human gene AnnexinA3, a human gene ATC code A03 Drugs for functional gastrointestinal...
and fungi). In humans, the annexins are found inside the cell. However some annexins (Annexin A1, Annexin A2, and Annexin A5) can be secreted from the...
Annexin A5 (or annexin V) is a cellular protein in the annexin group. In flow cytometry, annexin V is commonly used to detect apoptotic cells by its ability...
Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. Annexin 2 is involved in diverse cellular processes such...
Annexin A1, also known as lipocortin I, is a protein that is encoded by the ANXA1 gene in humans. Annexin A1 belongs to the annexin family of Ca2+-dependent...
Annexin A7 is a protein that in humans is encoded by the ANXA7 gene. Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding...
Annexin A11 is a protein that in humans is encoded by the ANXA11 gene. This gene encodes a member of the annexin family, a group of calcium-dependent...
associates with putative receptors such as alpha integrins, laminins, and annexin A2 leading to entry of the virions into basal epithelial cells through...
calcium-binding proteins, called EF hand proteins. The other group, called annexins, bind calcium and phospholipids such as lipocortin. Many other proteins...
PMID 15159548. Knop M, Aareskjold E, Bode G, Gerke V (2005). "Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial...
2006). "Regulation of ecto-5'-nucleotidase activity via Ca2+-dependent, annexin 2-mediated membrane rearrangement?". Biochemical Society Transactions....
NSCLC. Kinase insert domain receptor has been shown to interact with SHC2, Annexin A5 and SHC1. Cluster of differentiation VEGF receptors GRCh38: Ensembl...
Global Information
