Amfecloral information

Amfecloral
Clinical data
Other names	alpha-methyl-N-(2,2,2-trichloroethylidene)phenethylamine;; N-(2,2,2-trichloroethylidene)amphetamine
ATC code	none;
Legal status
Legal status	In general: unscheduled;
Identifiers
	IUPAC name 2,2,2-trichloro-N-(1-phenylpropan-2-yl)ethanimine;
CAS Number	5581-35-1 ;
PubChem CID	21759;
ChemSpider	20451 ;
UNII	6015XOA0BI;
KEGG	D02926 ;
ChEMBL	ChEMBL2105544 ;
Chemical and physical data
Formula	C11H12Cl3N
Molar mass	264.57 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES ClC(Cl)(Cl)/C=N/C(Cc1ccccc1)C;
	InChI InChI=1S/C11H12Cl3N/c1-9(15-8-11(12,13)14)7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3/b15-8+ ; Key:VBZDETYCYXPOAK-OVCLIPMQSA-N ;
	(what is this?) (verify)

Amfecloral (INN), also known as amphecloral (USAN), is a stimulant drug of the phenethylamine and amphetamine chemical classes that was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed.^[1] It was classified as an anorectic drug with little to no stimulant activity in a 1970 review.^[2] The British Pharmacopoeia Commission approved the name in 1970.^[3] The raw ingredients used in manufacturing it were d-amphetamine and chloral hydrate.^[4]

^ ^a ^b Ganellin CR, Triggle DJ (1996). Dictionary of pharmacological agents, Volumes 1-2. Chapman & Hall. p. 67. ISBN 9780412466304.
^ Van Rossum JM (1970). "Mode of action of psychomotor stimulant drugs". International Review of Neurobiology. 12: 307–83. doi:10.1016/s0074-7742(08)60065-3. ISBN 9780123668127. PMID 4918147.
^ "Notes and News". The Lancet. 296 (7675): 730–732. October 1970. doi:10.1016/S0140-6736(70)92010-6.
^ McPherson EM (2007). Pharmaceutical Manufacturing Encyclopedia (3rd ed.). Burlington: Elsevier. p. 244. ISBN 9780815518563.

[Ganellin-1] Ganellin CR, Triggle DJ (1996). Dictionary of pharmacological agents, Volumes 1-2. Chapman & Hall. p. 67. ISBN 9780412466304.

[2] Van Rossum JM (1970). "Mode of action of psychomotor stimulant drugs". International Review of Neurobiology. 12: 307–83. doi:10.1016/s0074-7742(08)60065-3. ISBN 9780123668127. PMID 4918147.

[3] "Notes and News". The Lancet. 296 (7675): 730–732. October 1970. doi:10.1016/S0140-6736(70)92010-6.

[4] McPherson EM (2007). Pharmaceutical Manufacturing Encyclopedia (3rd ed.). Burlington: Elsevier. p. 244. ISBN 9780815518563.

Amfecloral information

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