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List of withdrawn drugs information


Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e.g. lack of demand and relatively high production costs). Where risks or harms is the reason for withdrawal, this will usually have been prompted by unexpected adverse effects that were not detected during Phase III clinical trials, i.e. they were only made apparent from postmarketing surveillance data collected from the wider community over longer periods of time.

This list is not limited to drugs that were ever approved by the FDA. Some of them (lumiracoxib, rimonabant, tolrestat, ximelagatran and ximelidine, for example) were approved to be marketed in Europe but had not yet been approved for marketing in the US, when side effects became clear and their developers pulled them from the market. Some drugs in this list (e.g. LSD) were never approved for marketing in the US or Europe.

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List of withdrawn drugs

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Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e.g. lack of demand and...

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Lists of drugs

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hundreds of thousands of possible drugs. Any chemical substance with biological activity may be considered a drug. This list categorises drugs alphabetically...

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Pharmacology

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pharmaceutical companies List of withdrawn drugs Pharmaceutical company Pharmaceutical formulation Vallance P, Smart TG (January 2006). "The future of pharmacology"...

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Adverse drug reaction

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Iatrogenesis Lethal dose List of withdrawn drugs Paradoxical reaction Polypharmacy Toxicity Toxicology The Medical Letter on Drugs and Therapeutics Yellow...

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Postmarketing surveillance

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reporting List of withdrawn drugs McNeil JJ, Piccenna L, Ronaldson K, et al. (2010). "The Value of Patient-Centred Registries in Phase IV Drug Surveillance"...

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Outline of medicine

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Schedule I drugs List of Schedule II drugs List of Schedule III drugs List of Schedule IV drugs List of Schedule V drugs List of withdrawn drugs Medical...

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List of antiviral drugs

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Antiviral drugs are different from antibiotics. Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as...

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Drug recall

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using a product. A more comprehensive list of drug recalls worldwide can be found here: List of withdrawn drugs. Mrs. Winslow's Soothing Syrup introduced...

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Pharmacovigilance

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for Pharmacoepidemiology International Society of Pharmacovigilance List of withdrawn drugs Society of Pharmacovigilance, India (SoPI) MedDRA – Medical...

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Phenacetin

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PMID 10850471. "Phenacetin". DrugBank. Retrieved 28 April 2020. "Drugs withdrawn from the market containing phenacetin" (PDF). Department of Health and Human Services...

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List of antidepressants

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a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment...

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Adverse effect

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interaction EudraVigilance Evidence-based medicine List of pharmaceutical companies List of withdrawn drugs Medical algorithm Medical prescription Nocebo Patient...

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Etretinate

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due to the high risk of birth defects. In Japan, the drug remains on market branded Tigason. Isotretinoin List of withdrawn drugs Anvisa (2023-07-24)....

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Hepatotoxicity

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drugs have been implicated in causing liver injury (see LiverTox, external link, below) and it is the most common reason for a drug to be withdrawn from...

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Ingenol mebutate

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doi:10.1055/s-2000-8568. PMID 10821064. S2CID 260249228. "Drugs@FDA: FDA-Approved Drugs". Accessdata.fda.gov. Retrieved 10 April 2022. "Picato | European...

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Methaqualone

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for sleep. The drug was more tightly regulated in Britain under the Misuse of Drugs Act 1971 and in the U.S. from 1973. It was withdrawn from many developed...

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Trimetazidine

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balance of different ions and molecules within the cell. "Trimetazidine". Drugs.com. "European Medicines Agency recommends restricting use of trimetazidine-containing...

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Generic drug

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drugs are allowed for sale after the patents on the original drugs expire. Because the active chemical substance is the same, the medical profile of generics...

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Antipsychotic

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of drugs has a history of criticism in residential care. As the drugs used can make patients calmer and more compliant, critics claim that the drugs can...

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DrugBank

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Version 2.0 also included, for the first time, withdrawn drugs and illicit drugs, extensive food-drug and drug-drug interactions as well as ADMET (absorption...

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Rimonabant

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names Acomplia, Zimulti) is an anorectic antiobesity drug approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side...

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Dextropropoxyphene

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to be withdrawn from 1 March 2012, but Aspen Pharma sought a review in the Administrative Appeals Tribunal which ruled in 2013 that the drugs could be...

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Pure Food and Drug Act

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U.S. Department of Agriculture. The first federal law regulating foods and drugs, the 1906 Act's reach was limited to foods and drugs moving in interstate...

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List of aminorex analogues

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This is a list of aminorex analogues. Aminorex itself is a stimulant drug with a 5-phenyl-2-amino-oxazoline structure. It was developed in the 1960s as...

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