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Aminophenazone (or aminopyrine, amidopyrine, Pyramidon) is a non-narcotic analgesic substance. It is a pyrazolone and a derivative of phenazone, which also has anti-inflammatory and antipyretic properties. While inexpensive and effective, especially in the treatment of rheumatism, the drug carries a serious risk of severe and sometimes fatal side-effects, including agranulocytosis.[citation needed] While its production and use have been banned in many countries, including France, Thailand, India and Japan, it is still sometimes used in the developing world.[citation needed]
A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of cytochrome P-450 metabolic activity in liver-function tests.[1] It is also used in measuring the total body water in the human body system.[2]
^ abCaubet MS, Laplante A, Caillé J, Brazier JL (June 2002). "[13C]aminopyrine and [13C]caffeine breath test: influence of gender, cigarette smoking and oral contraceptives intake". Isotopes in Environmental and Health Studies. 38 (2): 71–7. Bibcode:2002IEHS...38...71C. doi:10.1080/10256010208033314. PMID 12219983. S2CID 22002940.
^"Aminophenazone — Compound Summary". PubChem. The National Library of Medicine. 2005-03-26. Retrieved June 12, 2008.
Aminophenazone (or aminopyrine, amidopyrine, Pyramidon) is a non-narcotic analgesic substance. It is a pyrazolone and a derivative of phenazone, which...
treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot...
as allobarbitone and branded as Dial, Cibalgine (in combination with aminophenazone), or Dial-Ciba (in combination with ethyl carbamate), is a barbiturate...
per diclofenac. PO. No data. Pain and inflammation. As diclofenac. Aminophenazone Related to phenylbutazone. As per diclofenac. PO. Not available. Musculoskeletal...
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