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Active ester information


In organic chemistry, an active ester is an ester functional group that is highly susceptible toward nucleophilic attack. Activation can be imparted by modifications of the acyl or the alkoxy components of a normal ester, say ethyl acetate. Typical modifications call for electronegative substituents. Active esters are employed in both synthetic and biological chemistry.

Acetyl CoA is the prototypical active ester in biosynthesis.

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Active ester

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In organic chemistry, an active ester is an ester functional group that is highly susceptible toward nucleophilic attack. Activation can be imparted by...

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HATU

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Uronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU is used along with Hünig's base (N,N-diisopropylethylamine...

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Pentafluorophenyl esters

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(PFP) esters are chemical compounds with the generic formula RC(O)OC6F5. They are active esters derived from pentafluorophenol (HOC6F5). PFP esters are...

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Ester Noronha

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Ester Valerie Noronha is an Indian actress who appears in Telugu and Kannada films. Her notable works include Bhimavaram  Bullodu, Shakeela, Lanke, Sophiya...

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Ester Dean

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Esther Renay Dean (born April 15, 1982), known professionally as Ester Dean, is an American R&B singer, songwriter, and record producer. She rose to prominence...

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Benzyl chloroformate

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chloroformate, also known as benzyl chlorocarbonate or Z-chloride, is the benzyl ester of chloroformic acid. It can be also described as the chloride of the benzyloxycarbonyl...

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Progestogen ester

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A progestogen ester is an ester of a progestogen or progestin (a synthetic progestogen). The prototypical progestogen is progesterone, an endogenous sex...

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Fluorophore

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attached to proteins to specific functional groups, such as amino groups (active ester, carboxylate, isothiocyanate, hydrazine), carboxyl groups (carbodiimide)...

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Peptide synthesis

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(HOAt). These reagents attack the O-acylisourea intermediate to form an active ester, which subsequently reacts with the peptide to form the desired peptide...

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Diamine

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for the synthesis of primary amides of amino acids and peptides from active esters". International Journal of Peptide and Protein Research. 42 (1): 53–57...

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Native chemical ligation

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amino acid thioester reactions led Wieland and others to develop the 'active ester' method for the synthesis of protected peptide segments by conventional...

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Sucrose esters

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Sucrose esters or sucrose fatty acid esters are a group of non-naturally occurring surfactants chemically synthesized from the esterification of sucrose...

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Polyester

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Polyester is a category of polymers that contain the ester functional group in every repeat unit of their main chain. As a specific material, it most...

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List of estrogen esters

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This is a list of estrogen esters, or ester prodrugs of estrogens. It includes esters, as well as ethers, of steroidal estrogens like estradiol, estrone...

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Creatine

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return to baseline in 4–6 weeks. Creatine supplements are marketed in ethyl ester, gluconate, monohydrate, and nitrate forms. Creatine supplementation for...

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List of progestogen esters

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medroxyprogesterone acetate, and nomegestrol acetate are active themselves and are not prodrugs, whereas esters of 19-nortestosterone derivatives like norethisterone...

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Hydrochloride

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acids. Glycine methyl ester hydrochloride is a shelf-stable salt that can be readily converted to a reactive glycine methyl ester, a compound that is not...

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DMTMM

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acid reacts with DMTMM to form the active ester, releasing a molecule of N-methylmorpholinium (NMM). The resulting ester is highly reactive and can undergo...

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Phenols

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versatile antioxidant. Phenols undergo esterification. Phenol esters are active esters, being prone to hydrolysis. Phenols are reactive species toward...

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Surfactant

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gas, or a liquid and a solid. The word "surfactant" is a blend of surface-active agent, coined c. 1950. As they consist of a water-repellent and a water-attracting...

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Acylation

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agents. In some cases, active esters exhibit comparable reactivity. All react with amines to form amides and with alcohols to form esters by nucleophilic acyl...

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Pentafluorophenol

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phenols. Pentafluorophenol is used to prepare pentafluorophenyl esters, which are active esters useful in peptide synthesis. Pentafluorophenol is considered...

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